about
Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulumThe coordination of cell growth during fission yeast mating requires Ras1-GTP hydrolysisImage based validation of dynamical models for cell reorientation.Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of ReceptorsDevelopment of a semi-quantitative plate-based alpha-galactosidase gene reporter for Schizosaccharomyces pombe and its use to isolate a constitutively active Mam2.The role of the RACK1 ortholog Cpc2p in modulating pheromone-induced cell cycle arrest in fission yeast.GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.Investigating RGS proteins in yeast.Feedback activation of neurofibromin terminates growth factor-induced Ras activation.Ras activation revisited: role of GEF and GAP systems.Receptor activity-modifying proteins; multifunctional G protein-coupled receptor accessory proteins.Modulation of Glucagon Receptor Pharmacology by Receptor Activity-modifying Protein-2 (RAMP2).Investigating G protein signalling bias at the glucagon-like peptide-1 receptor in yeast.Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors.Paracrine oxytocin and estradiol demonstrate a spatial increase in human intrauterine tissues with labor.Hyperglycaemia does not affect antigen-specific activation and cytolytic killing by CD8+ T cells in vivo.Identification of proteases with shared functions to the proprotein processing protease Krp1 in the fission yeast Schizosaccharomyces pombe.Quantitative analysis of human ras localization and function in the fission yeast Schizosaccharomyces pombe.Dual positive and negative regulation of GPCR signaling by GTP hydrolysis.Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases.Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor.Cortical oscillatory dynamics and benzodiazepine-site modulation of tonic inhibition in fast spiking interneurons.Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity.Parameter identification problems in the modelling of cell motility.The effects of RAMPs upon cell signalling.Regulators of G protein signalling proteins in the human myometrium.One motif to bind them: A small-XXX-small motif affects transmembrane domain 1 oligomerization, function, localization, and cross-talk between two yeast GPCRs.Heterologous expression of GPCRs in fission yeast.An efficient bipartite PCR technique to introduce specific changes in large plasmids.Emerging patents in the therapeutic areas of glioma and glioblastoma.Differential effects of RGS proteins on Gαq and Gα11 activityBCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinomaUtilisation of the budding yeastSaccharomyces cerevisiae for the generation and isolation of non-lethal ricin A chain variantsThe sxa2-dependent inactivation of the P-factor mating pheromone in the fission yeast Schizosaccharomyces pombeSxa2 is a serine carboxypeptidase that degrades extracellular P-factor in the fission yeast Schizosaccharomyces pombeA temperature-sensitive Krp1 allows in vivo characterization of kexin activationThe processing of yeast pheromonesExtracellular degradation of agonists as an adaptive mechanismIdentifying regulators of pheromone signalling in the fission yeast Schizosaccharomyces pombeCombined use of two transcriptional reporters improves signalling assays for G protein-coupled receptors in fission yeast
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Graham Ladds
@ast
Graham Ladds
@en
Graham Ladds
@es
Graham Ladds
@nl
Graham Ladds
@sl
type
label
Graham Ladds
@ast
Graham Ladds
@en
Graham Ladds
@es
Graham Ladds
@nl
Graham Ladds
@sl
prefLabel
Graham Ladds
@ast
Graham Ladds
@en
Graham Ladds
@es
Graham Ladds
@nl
Graham Ladds
@sl
P106
P1153
6603672356
P21
P31
P496
0000-0001-7320-9612
P569
2000-01-01T00:00:00Z