Rho-kinase inhibitor, fasudil, prevents neuronal apoptosis via the Akt activation and PTEN inactivation in the ischemic penumbra of rat brain.
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Selective ROCK2 inhibition in focal cerebral ischemiaThe role of the Rho/ROCK signaling pathway in inhibiting axonal regeneration in the central nervous systemModulating Astrocyte Transition after Stroke to Promote Brain Rescue and Functional Recovery: Emerging Targets Include Rho KinaseVinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytesThe ROCK Inhibitor Fasudil Prevents Chronic Restraint Stress-Induced Depressive-Like Behaviors and Dendritic Spine Loss in Rat HippocampusMyeloid PTEN deficiency protects livers from ischemia reperfusion injury by facilitating M2 macrophage differentiation.ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS.Rho kinase: A new target for treatment of cerebral ischemia/reperfusion injury.Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease.Renoprotective Effects of Atorvastatin in Diabetic Mice: Downregulation of RhoA and Upregulation of Akt/GSK3.Impacts of Rho kinase inhibitor Fasudil on Rho/ROCK signaling pathway in rabbits with optic nerve injury.Effects of Rho Kinase Inhibitors on Grafts of Dopaminergic Cell Precursors in a Rat Model of Parkinson's Disease.Caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury is mediated via RhoA and ROCK activation in major pelvic ganglion.Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.Fasudil, a rho kinase inhibitor, limits motor neuron loss in experimental models of amyotrophic lateral sclerosisEstrogen Regulates Protein Synthesis and Actin Polymerization in Hippocampal Neurons through Different Molecular Mechanisms.Neuroproteomics approach and neurosystems biology analysis: ROCK inhibitors as promising therapeutic targets in neurodegeneration and neurotrauma.Role of phosphatase and tensin homolog in hypoxic pulmonary vasoconstriction.Improving Reperfusion Therapies in the Era of Mechanical ThrombectomyInteraction between NADPH-oxidase and Rho-kinase in angiotensin II-induced microglial activation.Intravitreal Injection of a Rho-Kinase Inhibitor (Fasudil) for Recent-Onset Nonarteritic Anterior Ischemic Optic Neuropathy.Hydroxyl fasudil, an inhibitor of Rho signaling, improves erectile function in diabetic rats: a role for neuronal ROCK.Two PTP receptors mediate CSPG inhibition by convergent and divergent signaling pathways in neurons.Treatment with low dose fasudil for acute ischemic stroke in chronic hypertension.Antenatal taurine improves neuronal regeneration in fetal rats with intrauterine growth restriction by inhibiting the Rho-ROCK signal pathway.Role of Rho Kinase Inhibition in the Protective Effect of Fasudil and Simvastatin Against 3-Nitropropionic Acid-Induced Striatal Neurodegeneration and Mitochondrial Dysfunction in Rats.Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis.Upregulation of Gem relates to retinal ganglion cells apoptosis after optic nerve crush in adult rats.FSD-C10 Shows Therapeutic Effects in Suppressing oxidized low-density lipoprotein (ox-LDL)-Induced Human Brain Microvascular Endothelial Cells Apoptosis via Rho-Associated Coiled-Coil Kinase (ROCK)/Mitogen-Activated Protein Kinase (MAPK) Signaling
P2860
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P2860
Rho-kinase inhibitor, fasudil, prevents neuronal apoptosis via the Akt activation and PTEN inactivation in the ischemic penumbra of rat brain.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Rho-kinase inhibitor, fasudil, ...... schemic penumbra of rat brain.
@en
Rho-kinase inhibitor, fasudil, ...... schemic penumbra of rat brain.
@nl
type
label
Rho-kinase inhibitor, fasudil, ...... schemic penumbra of rat brain.
@en
Rho-kinase inhibitor, fasudil, ...... schemic penumbra of rat brain.
@nl
prefLabel
Rho-kinase inhibitor, fasudil, ...... schemic penumbra of rat brain.
@en
Rho-kinase inhibitor, fasudil, ...... schemic penumbra of rat brain.
@nl
P2093
P2860
P1476
Rho-kinase inhibitor, fasudil, ...... schemic penumbra of rat brain.
@en
P2093
Dongfang Wu
Jianhua Wu
Jianzhe Li
Yunxiang Fang
P2860
P2888
P304
P356
10.1007/S10571-012-9845-Z
P577
2012-05-03T00:00:00Z