RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

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The Receptor for Advanced Glycation Endproducts is a mediator of toxicity by IAPP and other proteotoxic aggregates: Establishing and Exploiting Common Ground for Novel Amyloidosis Therapies.

P2860

Q52583445-9D8A48B3-3E3B-4AD3-97B9-413E042980A6

P2860

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

Item

http://www.wikidata.org/entity/Q48536125

description

2018 nî lūn-bûn

@nan

2018年の論文

@ja

2018年学术文章

@wuu

2018年学术文章

@zh

2018年学术文章

@zh-cn

2018年学术文章

@zh-hans

2018年学术文章

@zh-my

2018年学术文章

@zh-sg

2018年學術文章

@yue

2018年學術文章

@zh-hant

name

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

@en

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

@nl

type

Item

label

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

@en

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

@nl

prefLabel

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

@en

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

@nl

P1476

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity

@en

P2093

Ann Marie Schmidt

http://www.w3.org/2001/XMLSchema#string

Annette Plesner

http://www.w3.org/2001/XMLSchema#string

Daniel P Raleigh

http://www.w3.org/2001/XMLSchema#string

Fei Song

http://www.w3.org/2001/XMLSchema#string

Jacqueline Lonier

http://www.w3.org/2001/XMLSchema#string

Jinghua Zhang

http://www.w3.org/2001/XMLSchema#string

Julia Derk

http://www.w3.org/2001/XMLSchema#string

Meilun He

http://www.w3.org/2001/XMLSchema#string

Ping Cao

http://www.w3.org/2001/XMLSchema#string

Rosa Rosario

http://www.w3.org/2001/XMLSchema#string

P2860

An amylin receptor is revealed following co-transfection of a calcitonin receptor with receptor activity modifying proteins-1 or -3

Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

Mechanisms of islet amyloidosis toxicity in type 2 diabetes

Development, growth and maintenance of β-cell mass: models are also part of the story

Protein misfolding, functional amyloid, and human disease

Inhibition of the receptor for advanced glycation endproducts (RAGE) protects pancreatic β-cells

P304

682-698

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P31

scholarly article

P356

10.1172/JCI85210

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

128

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P50

Hyunwook Koh

Andisheh Abedini

Huilin Li

P577

2018-01-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29337308

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P932

5785261

http://www.w3.org/2001/XMLSchema#string

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

about

P2860

P2860

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932