Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents. - Wikidata - awgldk - TriplyDB

Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.

Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.

http://www.wikidata.org/entity/Q48644864

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Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structure A conformational change in the peripheral anionic site of Torpedo californica acetylcholinesterase induced by a bis-imidazolium oxime A sensitive magnetic nanoparticle-based immunoassay of phosphorylated acetylcholinesterase using protein cage templated lead phosphate for signal amplification with graphite furnace atomic absorption spectrometry detection In silico studies in probing the role of kinetic and structural effects of different drugs for the reactivation of tabun-inhibited AChE Toxicology of organophosphorus compounds in view of an increasing terrorist threat.Neurological aspects of chemical and biological terrorism: guidelines for neurologists.LY293558 prevents soman-induced pathophysiological alterations in the basolateral amygdala and the development of anxiety.A rat model of nerve agent exposure applicable to the pediatric population: The anticonvulsant efficacies of atropine and GluK1 antagonists Low-cost bioanalysis on paper-based and its hybrid microfluidic platforms Efficacy of the GluK1/AMPA receptor antagonist LY293558 against seizures and neuropathology in a soman-exposure model without pretreatment and its pharmacokinetics after intramuscular administration Advances in toxicology and medical treatment of chemical warfare nerve agents Kinetic assessment of N-methyl-2-methoxypyridinium species as phosphonate anion methylating agents Efforts toward treatments against aging of organophosphorus-inhibited acetylcholinesterase.Novel brain-penetrating oximes for reactivation of cholinesterase inhibited by sarin and VX surrogates.New Cinchona Oximes Evaluated as Reactivators of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Organophosphorus Compounds.Post-exposure treatment with the oxime RS194B rapidly reverses early and advanced symptoms in macaques exposed to sarin vapor.SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides.Essential Lessons in a Potential Sarin Attack Disaster Plan for a Resource-Constrained Environment.Nerve Gas Simulant Sensing by a Uranyl-Salen Monolayer Covalently Anchored on Quartz Substrates.CYP/PON genetic variations as determinant of organophosphate pesticides toxicity.Cholinesterase reactivators and bioscavengers for pre- and post-exposure treatments of organophosphorus poisoning.Progress in acetylcholinesterase reactivators and in the treatment of organophosphorus intoxication: a patent review (2006-2016).Aging mechanism of soman inhibited acetylcholinesterase.In vitro reactivation kinetics of paraoxon- and DFP-inhibited electric eel AChE using mono- and bis-pyridinium oximes.Unbinding free energy of acetylcholinesterase bound oxime drugs along the gorge pathway from metadynamics-umbrella sampling investigation.Prophylactic administration of non-organophosphate cholinesterase inhibitors before acute exposure to organophosphates: assessment using terbufos sulfone.Post-exposure treatment with the oxime RS194B rapidly reactivates and reverses advanced symptoms of lethal inhaled paraoxon in macaques.Chemical approaches for detection and destruction of nerve agents.Oxime-mediated in vitro reactivation kinetic analysis of organophosphates-inhibited human and electric eel acetylcholinesterase.Structural modifications of dicationic acetylcholinesterase reactivators studied under ion-pairing mechanism in reversed-phase liquid chromatography.Docking Studies, Synthesis, and In-vitro Evaluation of Novel Oximes Based on Nitrones as Reactivators of Inhibited Acetylcholinesterase.Nanoparticle-based immunochromatographic test strip with fluorescent detector for quantification of phosphorylated acetylcholinesterase: an exposure biomarker of organophosphorus agents.In silico and in vitro evaluation of two novel oximes (K378 and K727) in comparison to K-27 and pralidoxime against paraoxon-ethyl intoxication.Unbinding of fluorinated oxime drug from the AChE gorge in polarizable water: a well-tempered metadynamics study.The role of multifunctional drug therapy as an antidote to combat experimental subacute neurotoxicity induced by organophosphate pesticides.On the Influence of the Protonation States of Active Site Residues on AChE Reactivation: A QM/MM Approach.The evaluation of the reactivating and therapeutic efficacy of three novel bispyridinium oximes (K454, K456, K458) in comparison with the oxime K203 and trimedoxime in tabun-poisoned rats and mice.Can hydroxylamine be a more potent nucleophile for the reactivation of tabun-inhibited AChE than prototype oxime drugs? An answer derived from quantum chemical and steered molecular dynamics studies.TRPA1 channel mediates organophosphate-induced delayed neuropathy.The reactivation of tabun-inhibited mutant AChE with Ortho-7: steered molecular dynamics and quantum chemical studies.

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P2860

Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.

http://www.wikidata.org/entity/Q48644864

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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name

Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.

@en

Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.

@nl

type

label

Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.

@en

Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.

@nl

prefLabel

Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.

@en

Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.

@nl

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Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.

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Florian Nachon

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Guillaume Mercey

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Julien Renou

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Maria Kliachyna

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Pierre-Yves Renard

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Rachid Baati

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Tristan Verdelet

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10.1021/AR2002864

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221856858

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22360473

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