Neuroserpin, a neuroprotective factor in focal ischemic stroke.
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Targeted disruption of SPI3/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to strokePhysiological and pathological roles of tissue plasminogen activator and its inhibitor neuroserpin in the nervous systemTissue-type plasminogen activator is a neuroprotectant in the central nervous systemRetina Is Protected by Neuroserpin from Ischemic/Reperfusion-Induced Injury Independent of Tissue-Type Plasminogen ActivatorDeficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammationAcyl-enzyme complexes between tissue-type plasminogen activator and neuroserpin are short-lived in vitroNeuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer diseaseSelective regulation of acid-sensing ion channel 1 by serine proteasesRegulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independentSerine proteases, serine protease inhibitors, and protease-activated receptors: roles in synaptic function and behaviorIdentification of a novel targeting sequence for regulated secretion in the serine protease inhibitor neuroserpin.Neonatal Hypoxia Ischaemia: Mechanisms, Models, and Therapeutic Challenges.The functional genome of CA1 and CA3 neurons under native conditions and in response to ischemia.Neuroserpin polymorphisms and stroke risk in a biracial population: the stroke prevention in young women studyActivation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke.Microglia and the urokinase plasminogen activator receptor/uPA system in innate brain inflammation.Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: critical role of matrix metalloproteinases and tissue-type plasminogen activatorInnate inflammatory responses in stroke: mechanisms and potential therapeutic targets.Progesterone and allopregnanolone attenuate blood-brain barrier dysfunction following permanent focal ischemia by regulating the expression of matrix metalloproteinases.Neuroserpin protects neurons from ischemia-induced plasmin-mediated cell death independently of tissue-type plasminogen activator inhibition.Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke.AAV-mediated overexpression of neuroserpin in the hippocampus decreases PSD-95 expression but does not affect hippocampal-dependent learning and memory.Tissue plasminogen activator-independent roles of neuroserpin in the central nervous system.Neuroprotective effect of neuroserpin in oxygen-glucose deprivation- and reoxygenation-treated rat astrocytes in vitro.Inflammatory Animal Model for Parkinson's Disease: The Intranigral Injection of LPS Induced the Inflammatory Process along with the Selective Degeneration of Nigrostriatal Dopaminergic Neurons.Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit.The complexity of tissue-type plasminogen activator: can serine protease inhibitors help in stroke management?Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein mediate cerebral ischemia-induced nuclear factor-kappaB pathway activation.Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain.Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein induce Akt phosphorylation in the ischemic brainMild hypothermia reduces tissue plasminogen activator-related hemorrhage and blood brain barrier disruption after experimental stroke.Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.The low-density lipoprotein receptor-related protein 1 mediates tissue-type plasminogen activator-induced microglial activation in the ischemic brainTherapeutic administration of plasminogen activator inhibitor-1 prevents hypoxic-ischemic brain injury in newborns.tPA Modulation of the Blood-Brain Barrier: A Unifying Explanation for the Pleiotropic Effects of tPA in the CNS.HuD binds to three AU-rich sequences in the 3'-UTR of neuroserpin mRNA and promotes the accumulation of neuroserpin mRNA and proteinpH-dependent stability of neuroserpin is mediated by histidines 119 and 138; implications for the control of beta-sheet A and polymerization.Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling.Glaucoma is associated with plasmin proteolytic activation mediated through oxidative inactivation of neuroserpin.Expression of neuroserpin in the visual cortex of the mouse during the developmental critical period.
P2860
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P2860
Neuroserpin, a neuroprotective factor in focal ischemic stroke.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Neuroserpin, a neuroprotective factor in focal ischemic stroke.
@en
Neuroserpin, a neuroprotective factor in focal ischemic stroke.
@nl
type
label
Neuroserpin, a neuroprotective factor in focal ischemic stroke.
@en
Neuroserpin, a neuroprotective factor in focal ischemic stroke.
@nl
prefLabel
Neuroserpin, a neuroprotective factor in focal ischemic stroke.
@en
Neuroserpin, a neuroprotective factor in focal ischemic stroke.
@nl
P2093
P356
P1476
Neuroserpin, a neuroprotective factor in focal ischemic stroke.
@en
P2093
Osterwalder T
Sonderegger P
P304
P356
10.1006/MCNE.2001.1028
P577
2001-11-01T00:00:00Z