Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor.
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Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?Getting in shape: controlling peptide bioactivity and bioavailability using conformational constraintsTransforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxinsResidues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRsLess is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1.Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3Therapeutic potential of conopeptides.Therapeutic conotoxins: a US patent literature survey.Discovery and optimization of peptide macrocycles.The role of disulfide bonds in structure and activity of chlorotoxin.Design, synthesis, and characterization of cyclic analogues of the iron regulatory peptide hormone hepcidin.Cyclization of the antimicrobial peptide gomesin with native chemical ligation: influences on stability and bioactivity.Enhancing the therapeutic potential of peptide toxins.α9-containing nicotinic acetylcholine receptors and the modulation of pain.Effects of cyclic lipodepsipeptide structural modulation on stability, antibacterial activity, and human cell toxicity.Rationally designed peptidomimetic modulators of aβ toxicity in Alzheimer's disease.Molecular Engineering of Conus Peptides as Therapeutic Leads.Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer.Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal PeptidesDiscovery of Peptide Drugs from Natural Sources
P2860
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P2860
Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Effects of cyclization on stab ...... receptor and GABA(B) receptor.
@en
Effects of cyclization on stab ...... receptor and GABA(B) receptor.
@nl
type
label
Effects of cyclization on stab ...... receptor and GABA(B) receptor.
@en
Effects of cyclization on stab ...... receptor and GABA(B) receptor.
@nl
prefLabel
Effects of cyclization on stab ...... receptor and GABA(B) receptor.
@en
Effects of cyclization on stab ...... receptor and GABA(B) receptor.
@nl
P50
P356
P1476
Effects of cyclization on stab ...... receptor and GABA(B) receptor.
@en
P2093
Brid Callaghan
Reena Halai
P304
P356
10.1021/JM201060R
P407
P577
2011-09-15T00:00:00Z