Dyrk1A influences neuronal morphogenesis through regulation of cytoskeletal dynamics in mammalian cortical neurons.
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Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability DisordersDYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down SyndromeCase report of novel DYRK1A mutations in 2 individuals with syndromic intellectual disability and a review of the literatureThe DCR protein TTC3 affects differentiation and Golgi compactness in neurons through specific actin-regulating pathwaysMeeting at the crossroads: common mechanisms in Fragile X and Down syndromeAlterations to dendritic spine morphology, but not dendrite patterning, of cortical projection neurons in Tc1 and Ts1Rhr mouse models of Down syndromeDYRK1A Controls HIV-1 Replication at a Transcriptional Level in an NFAT Dependent Manner.Molecular and cellular alterations in Down syndrome: toward the identification of targets for therapeuticsTen new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A.Gene dosage-dependent association of DYRK1A with the cytoskeleton in the brain and lymphocytes of down syndrome patients.Lighting a path: genetic studies pinpoint neurodevelopmental mechanisms in autism and related disorders.Combined Treatment With Environmental Enrichment and (-)-Epigallocatechin-3-Gallate Ameliorates Learning Deficits and Hippocampal Alterations in a Mouse Model of Down Syndrome.New Perspectives of Dyrk1A Role in Neurogenesis and Neuropathologic Features of Down SyndromeModelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21.Intracellular distribution of differentially phosphorylated dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A).Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a.Genetics studies indicate that neural induction and early neuronal maturation are disturbed in autism.Importance of gene dosage in controlling dendritic arbor formation during development.Improving Memory and Cognition in Individuals with Down Syndrome.Potential Role of Microtubule Stabilizing Agents in Neurodevelopmental Disorders.Harmine stimulates proliferation of human neural progenitors.Hippocampal Dendritic Spines Are Segregated Depending on Their Actin Polymerization.Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control.
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P2860
Dyrk1A influences neuronal morphogenesis through regulation of cytoskeletal dynamics in mammalian cortical neurons.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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name
Dyrk1A influences neuronal mor ...... in mammalian cortical neurons.
@en
Dyrk1A influences neuronal mor ...... in mammalian cortical neurons.
@nl
type
label
Dyrk1A influences neuronal mor ...... in mammalian cortical neurons.
@en
Dyrk1A influences neuronal mor ...... in mammalian cortical neurons.
@nl
prefLabel
Dyrk1A influences neuronal mor ...... in mammalian cortical neurons.
@en
Dyrk1A influences neuronal mor ...... in mammalian cortical neurons.
@nl
P2093
P2860
P50
P356
P1433
P1476
Dyrk1A influences neuronal mor ...... in mammalian cortical neurons
@en
P2093
P2860
P304
P356
10.1093/CERCOR/BHR362
P50
P577
2012-01-02T00:00:00Z