Increased Systemic Exposure and Stronger Cardiovascular and Metabolic Adverse Reactions to Fenoterol in Individuals with Heritable OCT1 Deficiency.

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Emerging Clinical Importance of Hepatic Organic Cation Transporter 1 (OCT1) in Drug Pharmacokinetics, Dynamics, Pharmacogenetic Variability, and Drug Interactions.Effects of genetic polymorphisms on the OCT1 and OCT2-mediated uptake of ranitidine.

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Increased Systemic Exposure and Stronger Cardiovascular and Metabolic Adverse Reactions to Fenoterol in Individuals with Heritable OCT1 Deficiency.

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2017 nî lūn-bûn

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2017年学术文章

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Increased Systemic Exposure an ...... ith Heritable OCT1 Deficiency.

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Increased Systemic Exposure an ...... ith Heritable OCT1 Deficiency.

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Item

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Increased Systemic Exposure an ...... ith Heritable OCT1 Deficiency.

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Increased Systemic Exposure an ...... ith Heritable OCT1 Deficiency.

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Increased Systemic Exposure an ...... ith Heritable OCT1 Deficiency.

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Increased Systemic Exposure an ...... ith Heritable OCT1 Deficiency.

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Increased Systemic Exposure an ...... ith Heritable OCT1 Deficiency.

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Johannes Matthaei

http://www.w3.org/2001/XMLSchema#string

Jürgen Brockmöller

http://www.w3.org/2001/XMLSchema#string

Mladen V Tzvetkov

http://www.w3.org/2001/XMLSchema#string

Sabrina Vogler

http://www.w3.org/2001/XMLSchema#string

Thomas Prukop

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Tina Seitz

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P2860

Adverse drug reactions to tocolytic treatment for preterm labour: prospective cohort study

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences

Genetically polymorphic OCT1: another piece in the puzzle of the variable pharmacokinetics and pharmacodynamics of the opioidergic drug tramadol.

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.

Effect of rare variants in ADRB2 on risk of severe exacerbations and symptom control during longacting β agonist treatment in a multiethnic asthma population: a genetic study.

OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.

OCT1 genetic variants influence the pharmacokinetics of morphine in children.

The use of beta-agonists and the risk of death and near death from asthma.

Withdrawal of fenoterol and the end of the New Zealand asthma mortality epidemic.

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scholarly article

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10.1002/CPT.812

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English

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Frank Faltraco

Sherin Pojar

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2017-08-09T00:00:00Z

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28791698

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Increased Systemic Exposure and Stronger Cardiovascular and Metabolic Adverse Reactions to Fenoterol in Individuals with Heritable OCT1 Deficiency.

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Increased Systemic Exposure and Stronger Cardiovascular and Metabolic Adverse Reactions to Fenoterol in Individuals with Heritable OCT1 Deficiency.

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P1433

P1476

P2093

P2860

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P407

P50

P577

P698

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P1433

P1476

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P31

P356

P407

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P577

P698