PERK is responsible for the increased phosphorylation of eIF2alpha and the severe inhibition of protein synthesis after transient global brain ischemia.
about
Regulatory proteins of eukaryotic initiation factor 2-alpha subunit (eIF2 alpha) phosphatase, under ischemic reperfusion and toleranceAcute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation.Perk gene dosage regulates glucose homeostasis by modulating pancreatic β-cell functions.NFkappaB in neurons? The uncertainty principle in neurobiologyIrreversible aggregation of protein synthesis machinery after focal brain ischemia.Irreversible translation arrest in the reperfused brain.Cardioprotective effects of Notoginsenoside R1 against ischemia/reperfusion injuries by regulating oxidative stress- and endoplasmic reticulum stress- related signaling pathways.Translation arrest and ribonomics in post-ischemic brain: layers and layers of players.Loss of endoplasmic reticulum Ca2+ homeostasis: contribution to neuronal cell death during cerebral ischemia.Crosstalk Between Endoplasmic Reticulum Stress, Oxidative Stress, and Autophagy: Potential Therapeutic Targets for Acute CNS Injuries.Regulation of mRNA following brain ischemia and reperfusion.Translational control by eIF2α in neurons: Beyond the stress response.Unfolded protein response in brain ischemia: A timely update.rAAV8-733-Mediated Gene Transfer of CHIP/Stub-1 Prevents Hippocampal Neuronal Death in Experimental Brain Ischemia.Modulation of AβPP and GSK3β by Endoplasmic Reticulum Stress and Involvement in Alzheimer's Disease.Calcineurin β protects brain after injury by activating the unfolded protein response.Calpain cleaves methionine aminopeptidase-2 in a rat model of ischemia/reperfusion.Caspase-4 is essential for saikosaponin a-induced apoptosis acting upstream of caspase-2 and γ-H2AX in colon cancer cells.The double-edged sword of endoplasmic reticulum stress in uremic sarcopenia through myogenesis perturbation.Consolidation of object recognition memory requires HRI kinase-dependent phosphorylation of eIF2α in the hippocampus.Activation of cell surface GRP78 decreases endoplasmic reticulum stress and neuronal death.
P2860
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P2860
PERK is responsible for the increased phosphorylation of eIF2alpha and the severe inhibition of protein synthesis after transient global brain ischemia.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
PERK is responsible for the in ...... ansient global brain ischemia.
@en
PERK is responsible for the in ...... ansient global brain ischemia.
@nl
type
label
PERK is responsible for the in ...... ansient global brain ischemia.
@en
PERK is responsible for the in ...... ansient global brain ischemia.
@nl
prefLabel
PERK is responsible for the in ...... ansient global brain ischemia.
@en
PERK is responsible for the in ...... ansient global brain ischemia.
@nl
P2093
P2860
P1476
PERK is responsible for the in ...... ransient global brain ischemia
@en
P2093
Barbara C McGrath
Cheri R Owen
Douglas R Cavener
Gary S Krause
Peichuan Zhang
P2860
P304
P356
10.1111/J.1471-4159.2005.03276.X
P407
P50
P577
2005-07-05T00:00:00Z