Cyclic penicillamine containing enkephalin analogs display profound delta receptor selectivities.
about
Development of neuropeptide drugs that cross the blood-brain barrier.Development and in vitro characterization of a novel bifunctional μ-agonist/δ-antagonist opioid tetrapeptide.CNS drug delivery: opioid peptides and the blood-brain barrierDesign, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists.Bioactive conformations of two seminal delta opioid receptor penta-peptides inferred from free-energy profilesCharacterization of [3H][2-D-penicillamine, 5-D-penicillamine]-enkephalin binding to delta opiate receptors in the rat brain and neuroblastoma--glioma hybrid cell line (NG 108-15).Exploring the Backbone of Enkephalins To Adjust Their Pharmacological Profile for the δ-Opioid Receptor.Synthesis and Opioid Activity of Tyr1 -ψ[(Z)CF=CH]-Gly2 and Tyr1 -ψ[(S)/(R)-CF3 CH-NH]-Gly2 Leu-enkephalin Fluorinated Peptidomimetics.Two delta opioid receptor subtypes are functional in single ventral tegmental area neurons, and can interact with the mu opioid receptor.Tyr1-ψ[( Z)CF═CH]-Gly2 Fluorinated Peptidomimetic Improves Distribution and Metabolism Properties of Leu-Enkephalin.
P2860
Q33569277-DCC3B9B2-AF8A-4D05-9EB7-29378EFA7753Q35621534-34D76E06-1746-417B-BCDE-B464E882FF71Q36439195-28475AEE-18FC-463E-AF73-D682CDB37033Q36628309-317BCE9D-B025-41D4-AC91-8400BE0FCB2CQ37265995-FFBFAECE-6F82-4E0B-8478-5EFC1252E618Q37685086-542BB3D8-6090-4C80-BF47-9C5CD9D0C4F1Q39631797-88DE1050-72A1-4FDB-9A7D-E92BFB65BFCAQ44343990-B4865E53-2C38-466F-AD58-1AFFC17F96FDQ44346788-B1AE4E7C-30BD-4421-9945-A199124CD962Q52592115-BCB84E16-605B-4F02-A4D3-A8CA79DF40B1
P2860
Cyclic penicillamine containing enkephalin analogs display profound delta receptor selectivities.
description
1983 nî lūn-bûn
@nan
1983年の論文
@ja
1983年学术文章
@wuu
1983年学术文章
@zh
1983年学术文章
@zh-cn
1983年学术文章
@zh-hans
1983年学术文章
@zh-my
1983年学术文章
@zh-sg
1983年學術文章
@yue
1983年學術文章
@zh-hant
name
Cyclic penicillamine containin ...... delta receptor selectivities.
@en
Cyclic penicillamine containin ...... delta receptor selectivities.
@nl
type
label
Cyclic penicillamine containin ...... delta receptor selectivities.
@en
Cyclic penicillamine containin ...... delta receptor selectivities.
@nl
prefLabel
Cyclic penicillamine containin ...... delta receptor selectivities.
@en
Cyclic penicillamine containin ...... delta receptor selectivities.
@nl
P2093
P1433
P1476
Cyclic penicillamine containin ...... delta receptor selectivities.
@en
P2093
Galligan JJ
Mosberg HI
Yamamura HI
P304
P356
10.1016/0024-3205(83)90538-6
P407
P478
33 Suppl 1
P577
1983-01-01T00:00:00Z