Idebenone treatment in Leber's hereditary optic neuropathy.
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Leber hereditary optic neuropathy: current perspectivesMitochondrial disorders: challenges in diagnosis & treatmentIdebenone protects against retinal damage and loss of vision in a mouse model of Leber's hereditary optic neuropathyA neurodegenerative perspective on mitochondrial optic neuropathiesIs there treatment for Leber hereditary optic neuropathy?Features of idebenone and related short-chain quinones that rescue ATP levels under conditions of impaired mitochondrial complex ITreatment strategies for inherited optic neuropathies: past, present and futureOxidative stress and mitochondrial dysfunction across broad-ranging pathologies: toward mitochondria-targeted clinical strategies.Medical management of hereditary optic neuropathies.The effects of idebenone on mitochondrial bioenergeticsIdebenone increases mitochondrial complex I activity in fibroblasts from LHON patients while producing contradictory effects on respiration.The optic nerve: a "mito-window" on mitochondrial neurodegenerationEffects of idebenone on color vision in patients with leber hereditary optic neuropathy.Trial end points and natural history in patients with G11778A Leber hereditary optic neuropathy : preparation for gene therapy clinical trial.Secondary post-geniculate involvement in Leber's hereditary optic neuropathyA Female Patient with Down Syndrome and Low-Penetrance Leber's Hereditary Optic Neuropathy.Leber Hereditary Optic Neuropathy - Therapeutic Challenges and Early Promise.Nuclear expression of mitochondrial ND4 leads to the protein assembling in complex I and prevents optic atrophy and visual loss.Potential compounds for the treatment of mitochondrial disease.Neuron-specific enolase is elevated in asymptomatic carriers of Leber's hereditary optic neuropathy.Cigarette toxicity triggers Leber's hereditary optic neuropathy by affecting mtDNA copy number, oxidative phosphorylation and ROS detoxification pathwaysEfficacy and Safety of rAAV2-ND4 Treatment for Leber's Hereditary Optic NeuropathyEvaluation of Leber's hereditary optic neuropathy patients prior to a gene therapy clinical trial.Retinal ganglion cell dysfunction in asymptomatic G11778A: Leber hereditary optic neuropathy.The clinical maze of mitochondrial neurologyDrugs and mitochondrial diseases: 40 queries and answers.Treatment of hereditary optic neuropathies.Chemical and technological delivery systems for idebenone: a review of literature production.Mitochondrial optic neuropathies: our travels from bench to bedside and back again.Novel therapeutic approaches for Leber's hereditary optic neuropathy.Mitochondrial dysfunction in central nervous system white matter disorders.Disturbed mitochondrial dynamics and neurodegenerative disorders.Leber Hereditary Optic Neuropathy: Bringing the Lab to the Clinic.Idebenone: A Review in Leber's Hereditary Optic Neuropathy.Targeting estrogen receptor β as preventive therapeutic strategy for Leber's hereditary optic neuropathy.A Review of Mitochondrial Optic Neuropathies: From Inherited to Acquired FormsTherapeutic strategies for Leber's hereditary optic neuropathy: A current update.Leber hereditary optic neuropathy: bridging the translational gap.Leber Hereditary Optic Neuropathy: A Mitochondrial Disease Unique in Many Ways.Evaluating the therapeutic potential of idebenone and related quinone analogues in Leber hereditary optic neuropathy.
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Idebenone treatment in Leber's hereditary optic neuropathy.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Idebenone treatment in Leber's hereditary optic neuropathy.
@en
Idebenone treatment in Leber's hereditary optic neuropathy.
@nl
type
label
Idebenone treatment in Leber's hereditary optic neuropathy.
@en
Idebenone treatment in Leber's hereditary optic neuropathy.
@nl
prefLabel
Idebenone treatment in Leber's hereditary optic neuropathy.
@en
Idebenone treatment in Leber's hereditary optic neuropathy.
@nl
P2093
P50
P356
P1433
P1476
Idebenone treatment in Leber's hereditary optic neuropathy
@en
P2093
Agostino Baruzzi
Alfredo Arrigo Sadun
Anna Maria De Negri
Divya Aggarwal
Federico Sadun
Massimo Zeviani
Michele Carbonelli
Pasquale Montagna
Piero Barboni
P356
10.1093/BRAIN/AWR180
P407
P50
P577
2011-08-02T00:00:00Z