about
Teixobactin and Its Analogues: A New Hope in Antibiotic Discovery.Local disruption of DNA-base stacking by bulky base surrogates.Xanthones as inhibitors of microsomal lipid peroxidation and TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs).Synthetic and novel biocatalytic resolution studies on (+/-)-5/6/7-acetoxy-4-aryl-3,4-dihydrocoumarins.Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 10: identification of inhibitors for the liver microsomal acetoxycoumarin: protein transacetylase.Simplified teixobactin analogues to target superbugs.Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities.Design and syntheses of highly potent teixobactin analogues against Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE) in vitro and in vivo.Efficient total syntheses and biological activities of two teixobactin analogues.Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of l-allo-enduracididine with its isosteres.Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding.Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant (MRSA)Polycyclic Aromatic DNA-Base Surrogates: High-Affinity Binding to an Adenine-Specific Base-Flipping DNA MethyltransferaseSerendipitous isolation of a disappearing conformational polymorph of succinic acid challenges computational polymorph predictionDNA-directed spatial assembly of photosynthetic light-harvesting proteinsAsymmetric PTC C-alkylation catalyzed by chiral derivatives of tartaric acid and aminophenols. Synthesis Of (R)- and (S)-alpha-methyl amino acidsMode of action of teixobactins in cellular membranes
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Ishwar Singh
@ast
Ishwar Singh
@en
Ishwar Singh
@es
Ishwar Singh
@nl
Ishwar Singh
@sl
type
label
Ishwar Singh
@ast
Ishwar Singh
@en
Ishwar Singh
@es
Ishwar Singh
@nl
Ishwar Singh
@sl
prefLabel
Ishwar Singh
@ast
Ishwar Singh
@en
Ishwar Singh
@es
Ishwar Singh
@nl
Ishwar Singh
@sl
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P106
P1960
g-IAE8YAAAAJ
P214
P31
P496
0000-0001-7822-1063
P734
P7859
lccn-n84021645