Identification of a proline residue as a transduction element involved in voltage gating of gap junctions.
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Mutations in the human connexin gene GJB3 cause erythrokeratodermia variabilisA missense mutation in the human connexin50 gene (GJA8) underlies autosomal dominant "zonular pulverulent" cataract, on chromosome 1qA novel GJA8 mutation is associated with autosomal dominant lamellar pulverulent cataract: further evidence for gap junction dysfunction in human cataractGating properties of gap junction channels assembled from connexin43 and connexin43 fused with green fluorescent proteinDissection of the molecular basis of pp60(v-src) induced gating of connexin 43 gap junction channels.Helix kinks are equally prevalent in soluble and membrane proteins.The cytoplasmic accumulations of the cataract-associated mutant, Connexin50P88S, are long-lived and form in the endoplasmic reticulum.Arginine-164-tryptophan substitution in connexin32 associated with X linked dominant Charcot-Marie-Tooth diseaseAnalysis of four connexin26 mutant gap junctions and hemichannels reveals variations in hexamer stability.Intramolecular interactions mediate pH regulation of connexin43 channelsPH regulation of connexin43: molecular analysis of the gating particleSingle channel behavior of recombinant beta 2 gap junction connexons reconstituted into planar lipid bilayers.Distinct behavior of connexin56 and connexin46 gap junctional channels can be predicted from the behavior of their hemi-gap-junctional channels.Biophysical properties of gap junction channels formed by mouse connexin40 in induced pairs of transfected human HeLa cellsThe role of a conserved proline residue in mediating conformational changes associated with voltage gating of Cx32 gap junctions.Molecular dissection of transjunctional voltage dependence in the connexin-32 and connexin-43 junctions.Innexins get into the gap.Functional analysis of selective interactions among rodent connexins.Critical role of conserved proline residues in the transmembrane segment 4 voltage sensor function and in the gating of L-type calcium channels.Connexin gene pathology.Gap junction channel gating.Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32Voltage-dependent conformational changes in connexin channelsGap junction proteins and the wiring (Rewiring) of neuronal circuits.The pattern of disulfide linkages in the extracellular loop regions of connexin 32 suggests a model for the docking interface of gap junctionsIdentification of amino acid residues lining the pore of a gap junction channelConnexin 35: a gap-junctional protein expressed preferentially in the skate retinaSite-directed mutagenesis reveals putative regions of protein interaction within the transmembrane domains of connexinsConformational changes in a pore-forming region underlie voltage-dependent "loop gating" of an unapposed connexin hemichannel.A novel "pearl box" cataract associated with a mutation in the connexin 46 (GJA3) gene.Structure of the gap junction channel and its implications for its biological functions.Control of neuronal morphology and connectivity: emerging developmental roles for gap junctional proteins.A structural and functional comparison of gap junction channels composed of connexins and innexinsLoss of function and impaired degradation of a cataract-associated mutant connexin50.Connections with connexins: the molecular basis of direct intercellular signaling.Where are the gates in gap junction channels?Mutation in the M1 domain of the acetylcholine receptor alpha subunit decreases the rate of agonist dissociation.Expression of a dominant negative mutant innexin in identified neurons and glial cells reveals selective interactions among gap junctional proteins.Application of SCAM (substituted cysteine accessibility method) to gap junction intercellular channels.Inversion of both gating polarity and CO2 sensitivity of voltage gating with D3N mutation of Cx50.
P2860
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P2860
Identification of a proline residue as a transduction element involved in voltage gating of gap junctions.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh-hant
name
Identification of a proline re ...... ltage gating of gap junctions.
@en
Identification of a proline re ...... ltage gating of gap junctions.
@nl
type
label
Identification of a proline re ...... ltage gating of gap junctions.
@en
Identification of a proline re ...... ltage gating of gap junctions.
@nl
prefLabel
Identification of a proline re ...... ltage gating of gap junctions.
@en
Identification of a proline re ...... ltage gating of gap junctions.
@nl
P2093
P356
P1433
P1476
Identification of a proline re ...... ltage gating of gap junctions.
@en
P2093
P2888
P304
P356
10.1038/365847A0
P407
P577
1993-10-01T00:00:00Z
P6179
1035932436