Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance.
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Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease PathwaysEmerging Roles of Toxin-Antitoxin Modules in Bacterial PathogenesisPersisters-as elusive as everStructure, Biology, and Therapeutic Application of Toxin-Antitoxin Systems in Pathogenic BacteriaTargeting an Essential GTPase Obg for the Development of Broad-Spectrum AntibioticsWake me when it's over - Bacterial toxin-antitoxin proteins and induced dormancyReactive oxygen species do not contribute to ObgE*-mediated programmed cell deathPhysiologic Stresses Reveal a Salmonella Persister State and TA Family Toxins Modulate Tolerance to These Stresses.Persistence Increases in the Absence of the Alarmone Guanosine Tetraphosphate by Reducing Cell Growth.Development of Persister-FACSeq: a method to massively parallelize quantification of persister physiology and its heterogeneity.RNA Futile Cycling in Model Persisters Derived from MazF AccumulationCoexpression of Escherichia coli obgE, Encoding the Evolutionarily Conserved Obg GTPase, with Ribosomal Proteins L21 and L27HigB of Pseudomonas aeruginosa Enhances Killing of Phagocytes by Up-Regulating the Type III Secretion System in Ciprofloxacin Induced Persister Cells.RnlB Antitoxin of the Escherichia coli RnlA-RnlB Toxin-Antitoxin Module Requires RNase HI for Inhibition of RnlA Toxin Activity.In vivo Host Environment Alters Pseudomonas aeruginosa Susceptibility to Aminoglycoside AntibioticsVoltage-gated calcium flux mediates Escherichia coli mechanosensation.Toxin-antitoxin systems in bacterial growth arrest and persistence.The Role of Efflux and Physiological Adaptation in Biofilm Tolerance and Resistance.Structural and biochemical analysis of Escherichia coli ObgE, a central regulator of bacterial persistence.Hypothesis: type I toxin-antitoxin genes enter the persistence field-a feedback mechanism explaining membrane homoeostasis.Mechanisms of bacterial persistence during stress and antibiotic exposure.Two regulatory RNA elements affect TisB-dependent depolarization and persister formation.Persistent Persister Misperceptions.RNA-based regulation in type I toxin-antitoxin systems and its implication for bacterial persistence.Sleeper cells: the stringent response and persistence in the Borreliella (Borrelia) burgdorferi enzootic cycle.Transcriptional Repressor PtvR Regulates Phenotypic Tolerance to Vancomycin in Streptococcus pneumoniae.Toxin-antitoxin systems and their role in disseminating and maintaining antimicrobial resistance.In Vitro Characterization of the Type I Toxin-Antitoxin System bsrE/SR5 from Bacillus subtilis.ATP-Dependent Persister Formation in Escherichia coli.Evolution of Pectobacterium Bacteriophage ΦM1 To Escape Two Bifunctional Type III Toxin-Antitoxin and Abortive Infection Systems through Mutations in a Single Viral Gene.Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control.Intrinsic GTPase activity of a ribosomal maturation protein CgtA is associated with its inter-domain movement: insights from MD simulations and biochemical studies.In Vitro Emergence of High Persistence upon Periodic Aminoglycoside Challenge in the ESKAPE PathogensA Single-Amino-Acid Substitution in Obg Activates a New Programmed Cell Death Pathway in Escherichia coli.A Mutant Isoform of ObgE Causes Cell Death by Interfering with Cell Division.Against the mainstream: the membrane-associated type I toxin BsrG from Bacillus subtilis interferes with cell envelope biosynthesis without increasing membrane permeability.Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazFA multistress responsive type I toxin-antitoxin system: bsrE/SR5 from the B. subtilis chromosome.RNA editing in bacteria recodes multiple proteins and regulates an evolutionarily conserved toxin-antitoxin system.Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells.
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P2860
Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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name
Obg and Membrane Depolarizatio ...... Leads to Antibiotic Tolerance.
@en
Obg and Membrane Depolarizatio ...... Leads to Antibiotic Tolerance.
@nl
type
label
Obg and Membrane Depolarizatio ...... Leads to Antibiotic Tolerance.
@en
Obg and Membrane Depolarizatio ...... Leads to Antibiotic Tolerance.
@nl
prefLabel
Obg and Membrane Depolarizatio ...... Leads to Antibiotic Tolerance.
@en
Obg and Membrane Depolarizatio ...... Leads to Antibiotic Tolerance.
@nl
P2093
P50
P1433
P1476
Obg and Membrane Depolarizatio ...... Leads to Antibiotic Tolerance
@en
P2093
Ana Carolina Fierro
Charlotte Claudia David
Cyrielle Ines Kint
Jan Michiels
Joran Elie Michiels
Liselot Dewachter
Maarten Jansen
Veerle Liebens
Wouter Joris Knapen
P356
10.1016/J.MOLCEL.2015.05.011
P50
P577
2015-06-04T00:00:00Z