Model-Based Discovery and Development of Biopharmaceuticals: A Case Study of Mavrilimumab.

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Model-Based Discovery and Development of Biopharmaceuticals: A Case Study of Mavrilimumab.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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Model-Based Discovery and Deve ...... A Case Study of Mavrilimumab.

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Model-Based Discovery and Deve ...... A Case Study of Mavrilimumab.

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Item

label

Model-Based Discovery and Deve ...... A Case Study of Mavrilimumab.

@en

Model-Based Discovery and Deve ...... A Case Study of Mavrilimumab.

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Model-Based Discovery and Deve ...... A Case Study of Mavrilimumab.

@en

Model-Based Discovery and Deve ...... A Case Study of Mavrilimumab.

@nl

P1476

Model-Based Discovery and Deve ...... A Case Study of Mavrilimumab.

@en

P2093

Bing Wang

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Chi-Yuan Wu

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Denise Jin

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Lorin Roskos

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Paolo Vicini

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P2860

Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology

Safety of biologics, lessons learnt from TGN1412

Basic Concepts in Population Modeling, Simulation, and Model-Based Drug Development

Cytokine expression in synovial membranes of patients with rheumatoid arthritis and osteoarthritis.

Effects of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers.

Mavrilimumab, a human monoclonal antibody targeting GM-CSF receptor-α, in subjects with rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase I, first-in-human study

Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis

Gm-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense.

The biology of granulocyte-macrophage colony-stimulating factor: effects on hematopoietic and nonhematopoietic cells.

Integrated pharmacokinetic, pharmacodynamic and immunogenicity profiling of an anti-CCL21 monoclonal antibody in cynomolgus monkeys.

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5-15

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scholarly article

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10.1002/PSP4.12245

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2017-08-24T00:00:00Z

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28836356

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5784736

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