Neddylation inhibitor MLN4924 induces G2 cell cycle arrest, DNA damage and sensitizes esophageal squamous cell carcinoma cells to cisplatin.

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Neddylation inhibitor MLN4924 induces G2 cell cycle arrest, DNA damage and sensitizes esophageal squamous cell carcinoma cells to cisplatin.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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Neddylation inhibitor MLN4924 ...... carcinoma cells to cisplatin.

@en

Neddylation inhibitor MLN4924 ...... carcinoma cells to cisplatin.

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Item

label

Neddylation inhibitor MLN4924 ...... carcinoma cells to cisplatin.

@en

Neddylation inhibitor MLN4924 ...... carcinoma cells to cisplatin.

@nl

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Neddylation inhibitor MLN4924 ...... carcinoma cells to cisplatin.

@en

Neddylation inhibitor MLN4924 ...... carcinoma cells to cisplatin.

@nl

P1476

Neddylation inhibitor MLN4924 ...... carcinoma cells to cisplatin.

@en

P2093

Peng Gao

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Peng Qin

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Ping Chen

http://www.w3.org/2001/XMLSchema#string

Shan Lin

http://www.w3.org/2001/XMLSchema#string

Shuaiheng Hou

http://www.w3.org/2001/XMLSchema#string

Shuo Li

http://www.w3.org/2001/XMLSchema#string

Tao Hu

http://www.w3.org/2001/XMLSchema#string

Yi Zhang

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Zhaoyang Shang

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Ziming Dong

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P2860

Regulation of cancer-related pathways by protein NEDDylation and strategies for the use of NEDD8 inhibitors in the clinic

Cullin neddylation and substrate-adaptors counteract SCF inhibition by the CAND1-like protein Lag2 in Saccharomyces cerevisiae.

Chemogenomic Study of Carboplatin in Saccharomyces cerevisiae: Inhibition of the NEDDylation Process Overcomes Cellular Resistance Mediated by HuR and Cullin Proteins

Ubiquitin E3 ligase CRL4(CDT2/DCAF2) as a potential chemotherapeutic target for ovarian surface epithelial cancer

Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Overcoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN4924

Phase I Study of the Novel Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (MLN4924) in Patients with Relapsed/Refractory Multiple Myeloma or Lymphoma.

Protein neddylation: beyond cullin-RING ligases.

Neddylation pathway is up-regulated in human intrahepatic cholangiocarcinoma and serves as a potential therapeutic target

P304

2583-2589

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scholarly article

P356

10.3892/OL.2017.7616

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P478

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2017-12-14T00:00:00Z

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29434977

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5777299

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