about
Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetesAmelioration of type 1 diabetes following treatment of non-obese diabetic mice with INGAP and lisofylline.Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model.Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes developmentInhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetesNonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetesThe unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.Noninvasive assessment of pancreatic beta-cell function in vivo with manganese-enhanced magnetic resonance imaging.Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure.Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets.Maintenance of Pdx1 mRNA translation in islet β-cells during the unfolded protein response.Minireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes.Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling.Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9.Elevations in Circulating Methylated and Unmethylated Preproinsulin DNA in New-Onset Type 1 Diabetes.Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cellsLoss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival.Detection of islet β-cell death in vivo by multiplex PCR analysis of differentially methylated DNA.Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains.Protective effects of polyamine depletion in mouse models of type 1 diabetes: implications for therapy.Measurement of Differentially Methylated INS DNA Species in Human Serum Samples as a Biomarker of Islet β Cell DeathMouse islet of Langerhans isolation using a combination of purified collagenase and neutral protease.Elevated unmethylated and methylated insulin DNA are unique markers of A+β+ ketosis prone diabetes.Molecular mechanisms of nonalcoholic fatty liver disease: Potential role for 12-lipoxygenase.Effects of combination therapy with dipeptidyl peptidase-IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes.Hypoglycemia in a Patient With a Polyhormonal Pancreatic Neuroendocrine Tumor With Evidence of Endocrine Progenitors.Longitudinal Intravital Imaging of Biosensor-labeled In Situ Islet Beta CellsCombined Analysis of GAD65, miR-375, and Unmethylated Insulin DNA Following Islet Transplantation in Patients With T1DHypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasisA Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Sarah A Tersey
@ast
Sarah A Tersey
@en
Sarah A Tersey
@es
Sarah A Tersey
@nl
Sarah A Tersey
@sl
type
label
Sarah A Tersey
@ast
Sarah A Tersey
@en
Sarah A Tersey
@es
Sarah A Tersey
@nl
Sarah A Tersey
@sl
prefLabel
Sarah A Tersey
@ast
Sarah A Tersey
@en
Sarah A Tersey
@es
Sarah A Tersey
@nl
Sarah A Tersey
@sl
P106
P21
P31
P496
0000-0003-0667-2361
P569
2000-01-01T00:00:00Z