MYC-dependent downregulation of telomerase by FLT3 inhibitors is required for their therapeutic efficacy on acute myeloid leukemia.

about

The Myc/Max/Mxd Network Is a Target of Mutated Flt3 Signaling in Hematopoietic Stem Cells in Flt3-ITD-Induced Myeloproliferative Disease

P2860

Q58699279-8A37AA9F-6D87-4F8C-B3C9-A4544A03C061

P2860

MYC-dependent downregulation of telomerase by FLT3 inhibitors is required for their therapeutic efficacy on acute myeloid leukemia.

Item

http://www.wikidata.org/entity/Q49722374

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh-hant

name

MYC-dependent downregulation o ...... acy on acute myeloid leukemia.

@en

MYC-dependent downregulation o ...... acy on acute myeloid leukemia.

@nl

type

Item

label

MYC-dependent downregulation o ...... acy on acute myeloid leukemia.

@en

MYC-dependent downregulation o ...... acy on acute myeloid leukemia.

@nl

prefLabel

MYC-dependent downregulation o ...... acy on acute myeloid leukemia.

@en

MYC-dependent downregulation o ...... acy on acute myeloid leukemia.

@nl

P1476

MYC-dependent downregulation o ...... acy on acute myeloid leukemia.

@en

P2093

Anh Nhi Tran

http://www.w3.org/2001/XMLSchema#string

Bingnan Li

http://www.w3.org/2001/XMLSchema#string

Jenny Dahlström

http://www.w3.org/2001/XMLSchema#string

Jingya Yu

http://www.w3.org/2001/XMLSchema#string

Magnus Björkholm

http://www.w3.org/2001/XMLSchema#string

Xiaolu Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation of the epiregulin gene

Telomerase modulates Wnt signalling by association with target gene chromatin

Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia.

Secondary mutations as mediators of resistance to targeted therapy in leukemia

Regulation of the human catalytic subunit of telomerase (hTERT).

Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging.

Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells.

Clinical implications of FLT3 mutations in pediatric AML.

Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse.

Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns

P304

63-72

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S00277-017-3158-8

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Dawei Xu

P577

2017-10-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29080039

http://www.w3.org/2001/XMLSchema#string

P932

5748426

http://www.w3.org/2001/XMLSchema#string

MYC-dependent downregulation of telomerase by FLT3 inhibitors is required for their therapeutic efficacy on acute myeloid leukemia.

about

P2860

P2860

MYC-dependent downregulation of telomerase by FLT3 inhibitors is required for their therapeutic efficacy on acute myeloid leukemia.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932