Population Pharmacokinetic Modeling of Guselkumab, a Human IgG1λ Monoclonal Antibody Targeting IL-23, in Patients with Moderate to Severe Plaque Psoriasis.

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Population pharmacokinetics and exposure-response modeling and simulation for evolocumab in healthy volunteers and patients with hypercholesterolemia.

P2860

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P2860

Population Pharmacokinetic Modeling of Guselkumab, a Human IgG1λ Monoclonal Antibody Targeting IL-23, in Patients with Moderate to Severe Plaque Psoriasis.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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Population Pharmacokinetic Mod ...... te to Severe Plaque Psoriasis.

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Population Pharmacokinetic Mod ...... te to Severe Plaque Psoriasis.

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Population Pharmacokinetic Mod ...... te to Severe Plaque Psoriasis.

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Population Pharmacokinetic Mod ...... te to Severe Plaque Psoriasis.

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Population Pharmacokinetic Mod ...... te to Severe Plaque Psoriasis.

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Population Pharmacokinetic Mod ...... te to Severe Plaque Psoriasis.

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P1476

Population Pharmacokinetic Mod ...... ate to Severe Plaque Psoriasis

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P2093

Amarnath Sharma

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Bruce Randazzo

http://www.w3.org/2001/XMLSchema#string

Chuanpu Hu

http://www.w3.org/2001/XMLSchema#string

Honghui Zhou

http://www.w3.org/2001/XMLSchema#string

Yang Chen

http://www.w3.org/2001/XMLSchema#string

Yasmine Wasfi

http://www.w3.org/2001/XMLSchema#string

Zhenhua Xu

http://www.w3.org/2001/XMLSchema#string

Zhenling Yao

http://www.w3.org/2001/XMLSchema#string

P2860

New and emerging biologic therapies for moderate-to-severe plaque psoriasis: mechanistic rationales and recent clinical data for IL-17 and IL-23 inhibitors

Ways to fit a PK model with some data below the quantification limit.

Cytokine requirements for the differentiation and expansion of IL-17A- and IL-22-producing human Vgamma2Vdelta2 T cells.

The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses.

Population pharmacokinetics of therapeutic monoclonal antibodies.

IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases.

Efficacy and safety of guselkumab, an anti-interleukin-23 monoclonal antibody, compared with adalimumab for the treatment of patients with moderate to severe psoriasis with randomized withdrawal and retreatment: Results from the phase III, double-bl

Efficacy and safety of guselkumab, an anti-interleukin-23 monoclonal antibody, compared with adalimumab for the continuous treatment of patients with moderate to severe psoriasis: Results from the phase III, double-blinded, placebo- and active compa

Improvement in latent variable indirect response modeling of multiple categorical clinical endpoints: application to modeling of guselkumab treatment effects in psoriatic patients.

Composition of innate lymphoid cell subsets in the human skin: enrichment of NCR(+) ILC3 in lesional skin and blood of psoriasis patients.

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613-627

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scholarly article

meta-analysis

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10.1002/JCPH.1063

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Yaowei Zhu

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2018-01-17T00:00:00Z

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29341192

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Population Pharmacokinetic Modeling of Guselkumab, a Human IgG1λ Monoclonal Antibody Targeting IL-23, in Patients with Moderate to Severe Plaque Psoriasis.

about

P2860

P2860

Population Pharmacokinetic Modeling of Guselkumab, a Human IgG1λ Monoclonal Antibody Targeting IL-23, in Patients with Moderate to Severe Plaque Psoriasis.

description

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P433

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P50

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P698