Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.

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Oligodendrogliomas, IDH-mutant and 1p/19q-codeleted, arising during teenage years often lack TERT promoter mutation that is typical of their adult counterparts

P2860

Q58720681-7A9514C3-21FB-4B3F-A64E-03D5AFA80F0A

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Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.

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http://www.wikidata.org/entity/Q50051453

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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Deep sequencing of WNT-activat ...... ondary SHH pathway activation.

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Deep sequencing of WNT-activat ...... ondary SHH pathway activation.

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type

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Deep sequencing of WNT-activat ...... ondary SHH pathway activation.

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Deep sequencing of WNT-activat ...... ondary SHH pathway activation.

@nl

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Deep sequencing of WNT-activat ...... ondary SHH pathway activation.

@en

Deep sequencing of WNT-activat ...... ondary SHH pathway activation.

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P1476

Deep sequencing of WNT-activat ...... condary SHH pathway activation

@en

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Andrew W Bollen

http://www.w3.org/2001/XMLSchema#string

Andrey Korshunov

http://www.w3.org/2001/XMLSchema#string

Anuradha Banerjee

http://www.w3.org/2001/XMLSchema#string

Arie Perry

http://www.w3.org/2001/XMLSchema#string

Boris C Bastian

http://www.w3.org/2001/XMLSchema#string

Damian Stichel

http://www.w3.org/2001/XMLSchema#string

David Samuel

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James P Grenert

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Jessica Van Ziffle

http://www.w3.org/2001/XMLSchema#string

Marcel Kool

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P2860

Dissecting the genomic complexity underlying medulloblastoma

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas.

Medulloblastoma comprises four distinct molecular variants.

Intertumoral Heterogeneity within Medulloblastoma Subgroups.

Spatial heterogeneity in medulloblastoma.

The whole-genome landscape of medulloblastoma subtypes.

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s00401-018-1819-x

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635-638

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scholarly article

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10.1007/S00401-018-1819-X

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http://www.w3.org/2001/XMLSchema#string

P478

135

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Ivo Buchhalter

Lukas Chavez

Theodore P Nicolaides

J. Bryan Iorgulescu

David A Solomon

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2018-02-12T00:00:00Z

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29435664

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6078208

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Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.

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P2860

P2860

Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.

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P1476

P2093

P2860

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P932