Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children.

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Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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name

Predictive Performance of Phys ...... Cytochrome P450s in Children.

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Predictive Performance of Physiologically Based Pharmacokinetic

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label

Predictive Performance of Phys ...... Cytochrome P450s in Children.

@en

Predictive Performance of Physiologically Based Pharmacokinetic

@nl

prefLabel

Predictive Performance of Phys ...... Cytochrome P450s in Children.

@en

Predictive Performance of Physiologically Based Pharmacokinetic

@nl

P1476

Predictive Performance of Phys ...... Cytochrome P450s in Children.

@en

P2093

Diansong Zhou

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Hongmei Xu

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Jianguo Li

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Khanh H Bui

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Nidal Al-Huniti

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S Y Amy Cheung

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Trevor N Johnson

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Wangda Zhou

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P2860

Physiologically Based Pharmacokinetic Predictions of Tramadol Exposure Throughout Pediatric Life: an Analysis of the Different Clearance Contributors with Emphasis on CYP2D6 Maturation.

The Simcyp population-based ADME simulator

A re-evaluation and validation of ontogeny functions for cytochrome P450 1A2 and 3A4 based on in vivo data.

Prediction of in vivo drug clearance from in vitro data. I: impact of inter-individual variability.

Desloratadine has no clinically relevant electrocardiographic or pharmacodynamic interactions with ketoconazole.

Cytochrome p450 and chemical toxicology.

Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children.

Physiologically based pharmacokinetic modeling and simulation in pediatric drug development

Simultaneous assessment of drug interactions with low- and high-extraction opioids: application to parecoxib effects on the pharmacokinetics and pharmacodynamics of fentanyl and alfentanil.

Physiologically based pharmacokinetic (PBPK) modeling of caffeine and theophylline in neonates and adults: implications for assessing children's risks from environmental agents.

P31

scholarly article

P356

10.1002/CPT.905

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P407

English

P577

2017-10-13T00:00:00Z

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P698

29027194

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