NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency.

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Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States.PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD levels and increasing SIRT1 activity

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NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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NAD+ supplementation normalize ...... roduced DNA repair deficiency.

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NAD+ supplementation normalize ...... roduced DNA repair deficiency.

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NAD+ supplementation normalize ...... roduced DNA repair deficiency.

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NAD+ supplementation normalize ...... roduced DNA repair deficiency.

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NAD+ supplementation normalize ...... roduced DNA repair deficiency.

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Beverly A Baptiste

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Deborah L Croteau

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Eduardo Zavala

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Jennifer F O'Connell

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Kanako Moritoh

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Stephanie Cordonnier

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Tinna V Stevnsner

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Vilhelm A Bohr

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Yongqing Zhang

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Yue Wang

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P2860

Down syndrome as a model of DNA polymerase beta haploinsufficiency and accelerated aging

KEGG: Kyoto Encyclopedia of Genes and Genomes

PAGE: parametric analysis of gene set enrichment

Activation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing loss

A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

Morris water maze: procedures for assessing spatial and related forms of learning and memory

Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds

The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior

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scholarly article

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10.1073/PNAS.1718819115

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English

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115

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Yujun Hou

Sofie Lautrup

Mark Mattson

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2018-02-05T00:00:00Z

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29432159

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Alzheimer's disease

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5828618

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NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency.

about

P2860

P2860

NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency.

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