GroEL and GroES control of substrate flux in the in vivo folding pathway of phage P22 coat protein.
about
'Let the phage do the work': using the phage P22 coat protein structures as a framework to understand its folding and assembly mutantsA scFv antibody mutant isolated in a genetic screen for improved export via the twin arginine transporter pathway exhibits faster folding.Highly specific salt bridges govern bacteriophage P22 icosahedral capsid assembly: identification of the site in coat protein responsible for interaction with scaffolding protein.Sequence of the genome of Salmonella bacteriophage P22Co-production of GroELS discriminates between intrinsic and thermally-induced recombinant protein aggregation during substrate quality control.Molecular chaperones and selection against mutationsAn intramolecular chaperone inserted in bacteriophage P22 coat protein mediates its chaperonin-independent folding.GroEL binds a late folding intermediate of phage P22 coat protein.GroEL/S substrate specificity based on substrate unfolding propensity.Alleviation of a defect in protein folding by increasing the rate of subunit assembly.A concerted mechanism for the suppression of a folding defect through interactions with chaperones.Single amino acid substitutions globally suppress the folding defects of temperature-sensitive folding mutants of phage P22 coat protein.
P2860
Q30494291-CA5CC673-BDA7-4A1A-8DCA-EAE8F4FA0B36Q33282948-F59EBD5D-ABA5-4DEA-8807-79E172A46A2AQ33602778-49C0489A-02B9-4B29-9FD6-B4DFF38015BEQ33994952-9B9DB8BF-F2B7-4084-A8D7-979DEEC5878AQ35520931-52934B31-2E26-4924-98EC-EAAEF217D32DQ36496399-438EB760-528E-446F-980C-03AB2B1FC9B3Q37333736-C8DCD309-233E-41C4-B3CA-99B0BF9ACDC6Q40424851-1F3C9C67-580C-456F-B6A7-AE1263020A42Q42104362-6F194966-ADC0-4094-8BE2-82C31EC24248Q43576570-4F907896-A879-4143-9158-02D60A92050BQ44756926-4328B325-4833-4267-B393-AEF69EA3F8B3Q50125329-485BADD0-55D6-4C3F-B480-3AB17002711D
P2860
GroEL and GroES control of substrate flux in the in vivo folding pathway of phage P22 coat protein.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
GroEL and GroES control of sub ...... way of phage P22 coat protein.
@en
GroEL and GroES control of sub ...... way of phage P22 coat protein.
@nl
type
label
GroEL and GroES control of sub ...... way of phage P22 coat protein.
@en
GroEL and GroES control of sub ...... way of phage P22 coat protein.
@nl
prefLabel
GroEL and GroES control of sub ...... way of phage P22 coat protein.
@en
GroEL and GroES control of sub ...... way of phage P22 coat protein.
@nl
P2860
P356
P1476
GroEL and GroES control of sub ...... way of phage P22 coat protein.
@en
P2093
Nakonechny WS
Teschke CM
P2860
P304
27236-27244
P356
10.1074/JBC.273.42.27236
P407
P577
1998-10-01T00:00:00Z