Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.
about
New developments for protein quality control.The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions.Targeting multiple nodes of MLL complexes to improve leukemia therapy.Inflammatory Signaling Pathways in Preleukemic and Leukemic Stem Cells.The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability.Targeting oncoproteins for degradation by small molecules in myeloid leukemia.Unravelling the biology of chromatin in health and cancer using proteomic approaches.UBE2O is a quality control factor for orphans of multiprotein complexes.UBE2O remodels the proteome during terminal erythroid differentiation.Suppressing oncogenic transcription with a little healthy competition.Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin.New Insights into the Role of E2s in the Pathogenesis of Diseases: Lessons Learned from UBE2O.The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy
P2860
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P2860
Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.
description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
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2017年學術文章
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2017年學術文章
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name
Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.
@en
Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.
@nl
type
label
Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.
@en
Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.
@nl
prefLabel
Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.
@en
Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.
@nl
P2093
P2860
P50
P1433
P1476
Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.
@en
P2093
Ali Shilatifard
Andrew G Volk
Ashley R Woodfin
Edwin R Smith
Jeffrey S Haug
Jiwang Zhang
Joaquin M Espinosa
Joseph Cannova
Joshua M Gilmore
Kaiwei Liang
P2860
P304
P356
10.1016/J.CELL.2016.12.011
P407
P577
2017-01-02T00:00:00Z