Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment.
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Mechanisms of multistep carcinogenesis and carcinogen risk assessmentA perspective on nonmutagenic mechanisms in carcinogenesisReactive metabolites in the biotransformation of molecules containing a furan ringAbsence of ras family point mutations at codons 12, 13 and 61 in N-ethyl-N-hydroxyethylnitrosamine- or N-nitrosomorpholine-induced renal cell tumors in ratsCarcinogenicity of 1,3-butadienePerspectives on the risk assessment for nongenotoxic carcinogens and tumor promotersData requirements for risk assessment of furan in food.Genetic alterations in K-ras and p53 cancer genes in lung neoplasms from B6C3F1 mice exposed to cumene.Development of a highly efficient expression cDNA cloning system: application to oncogene isolation.Tumorigenic methylcholanthrene transformants of C3H/10T1/2 cells have a common nucleotide alteration in the c-Ki-ras gene.c-myc gene amplification during hepatocarcinogenesis by a choline-devoid diet.Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse.Metabolic activation capacity of neonatal mice in relation to the neonatal mouse tumorigenicity bioassay.Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetateMolecular analysis of O6-substituted guanine-induced mutagenesis of ras oncogenesMutagenicity of furan in female Big Blue B6C3F1 miceCellular and molecular mechanisms of multistep carcinogenesis: relevance to carcinogen risk assessmentIssues in biochemical applications to risk assessment: how do we evaluate individual components of multistage models?Oncogene activation in spontaneous and chemically induced rodent tumors: implications for risk analysisCan laboratory animal carcinogenicity studies predict cancer in exposed children?Carcinogenesis studies in rodents for evaluating risks associated with chemical carcinogens in aquatic food animalsRole of proto-oncogene activation in carcinogenesis.Radiation and chemical activation of ras oncogenes in different mouse strains.Growth-related alterations during liver carcinogenesis: effect of promotersThe role of non-ras transforming genes in chemical carcinogenesisActivation of proto-oncogenes in human and mouse lung tumorsMinimal cooperation between mutant Hras and c-myc or TGFα in the regulation of mouse hepatocyte growth or transformation in vivo.Mutant Hras(G12V) and Kras(G12D) have overlapping, but non-identical effects on hepatocyte growth and transformation frequency in transgenic miceN-nitroso-N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hras1 gene mutations.Hepatitis B virus infection and primary hepatocellular carcinoma.Nonrandom cytogenetic alterations in hepatocellular carcinoma from transgenic mice overexpressing c-Myc and transforming growth factor-alpha in the liver.Activation of the c-Ki-ras oncogene in aflatoxin B1-induced hepatocellular carcinoma and adenoma in the rat: detection by denaturing gradient gel electrophoresis.Electrophilic intermediates produced by bioactivation of furan.Neutron radiation can activate K-ras via a point mutation in codon 146 and induces a different spectrum of ras mutations than does gamma radiationConcomitant K- and N-ras gene point mutations in clonal murine lymphomaA new RAS mutation that suppresses the CDC25 gene requirement for growth of Saccharomyces cerevisiae.Tumorigenicity of simian virus 40-hepatocyte cell lines: effect of in vitro and in vivo passage on expression of liver-specific genes and oncogenes.Detection of DNA adducts derived from the reactive metabolite of furan, cis-2-butene-1,4-dial.Oncogenes and radiation carcinogenesisMutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis
P2860
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P2860
Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh-hant
name
Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment.
@en
Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment.
@nl
type
label
Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment.
@en
Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment.
@nl
prefLabel
Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment.
@en
Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment.
@nl
P2093
P356
P1433
P1476
Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment.
@en
P2093
Aaronson SA
Anderson MW
Maronpot RR
Patterson RM
Reynolds SH
Stowers SJ
P304
P356
10.1126/SCIENCE.3629242
P407
P577
1987-09-01T00:00:00Z