about
Stalling of DNA replication fork and RPA bindingRPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981;Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1;DNA2:BLM;WRN:p-S990;Ac-K1249-BRIP1RPA complexed to ssDNAProcessive complex:Okazaki fragment:Flap:RPA heterotrimerProcessive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimerMeiotic single-stranded DNA complexMeiotic D-loop complexMeiotic Holliday JunctionHSF1:RPAPCNA:POLD;POLE:RPA:RFCMonoUb:K164-PCNA:RPA:RFCPCNA:RPA:RFC:Damaged DNA TemplateMonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA TemplateDNA polymerase Y:MonoUb:K164;ISG:K164;ISG:K168-PCNA:RPA:RFC:TLS-DNA TemplateISG:K164;ISG:K168-PCNA:RPA:RFC:TLS-DNA TemplatePCNA:RPA:RFC:TLS-DNA TemplateGG-NER pre-incision complex:Open bubble-dsDNAGG-NER incision complex:5'-incised damaged DNA(PCNA:POLD;POLE); (MonoUb:K164-PCNA:POLK):RPA:RFCTC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNATC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNARPA:DNA containing single strand gapFANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIPRPA binds to the FlapRemoval of RNA primer and dissociation of RPA and Dna2RPA binds to the Flap on the C-strandRemoval of RNA primer and dissociation of RPA and Dna2 from the C-strandFormation of meiotic single-stranded DNA invasion complexResolution of meiotic holliday junctionHSF1 trimer binds HSE on the target geneRPA1 binds HSF1Association of RPA complexes with ssDNA at resected DNA DSBsPPP4C:PPP4R2 dephosphorylates RPA2Formation of the pre-incision complex in GG-NERERCC5 and RPA bind TC-NER siteEXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatchDNA polymerase delta polymerizes DNA across single stranded gapEXO1 interacting with MSH2:MSH3 excises DNA strand containing an insertion/deletion loop (IDL)The complex of ATR and ATRIP is recruited to ICL-DNA
P527
Q36813071-3DFFC3E8-F3A6-47D8-AB85-F56536105750Q50250609-87CD3627-F6E8-4DDE-9F06-1C9E45BD9BFAQ50250655-5612036D-6286-4172-B2C2-890962643DF9Q50250977-5ED5DEE7-F14A-4BA7-910A-ADC85B5EBA64Q50251533-4B9708C2-2CB1-4219-B15F-43F00F0B07B8Q50251575-227E0AB4-B6A5-48B4-A081-62F9F141BD65Q50251579-2E4D66EC-2C2D-46C8-994F-B32DE9A0A68EQ50251584-16453F55-0378-4D0B-B362-021F4075738FQ50252291-8457EA94-F9CD-49D0-AFE1-5F70F257EEEEQ50253204-5EEBF831-BA83-451C-8A22-904228F74B62Q50253246-EA960694-B182-49D8-8209-E63DA3BD2E4EQ50253258-B176DA07-4D3D-457B-8E6B-C7A2B2D914EBQ50253280-06736101-CFE7-4C6E-8152-D67BD016623FQ50253350-DC2A45B8-03F9-41DF-A7A2-53A16A916567Q50253356-B5F189F9-41C6-459E-AC5E-235FD725A170Q50253363-313FA152-5B9C-4B36-8F6E-141A4AEBDF4DQ50253740-9AD79940-00A0-42A2-BC7E-C3502D9C7C6FQ50253745-5A8A93A5-9782-43DE-87AC-50A802ED927EQ50253754-8D1084B2-897E-4FE4-9637-F51CA4046198Q50253815-20AA5A99-D320-4E78-BF2D-8CDA58339A47Q50253820-35A95633-115E-4927-8136-98ED91E1CB3BQ50253846-92A85062-E1D8-42A6-BA67-B2C8957F788DQ50253876-14CD2D46-E49F-474B-BF56-594BEB01ED83Q50286078-9A17C074-B79E-4E78-AFE0-15A8ECAF711AQ50286082-A0C45589-E619-4B30-8207-4C20A043790EQ50286330-7DD33B84-E423-4EC5-A887-C6560CB61106Q50286332-9D29F3B4-701A-4F03-9F15-0A9896B3AD63Q50286348-B919EE9B-179F-4DEF-8B9C-AB6249DDE4A0Q50286352-02B9BD4C-4449-4279-AB1D-E55D99D2745CQ50286609-C2C82046-389F-4903-AE7E-DA52CCF9B621Q50286623-2BFCE6E6-A6F1-4470-85E4-BCB5A3D685FAQ50287353-F6C0117D-4493-4AF3-ADF8-AD70D0112226Q50287359-9FF118A0-A11E-43FA-9C69-6DFA49BDAA28Q50287423-41392F20-2097-442F-BE86-48903679B66FQ50287441-DC9A4EA3-A1DB-43A5-914D-983F65082740Q50287458-D6464A5F-B694-40D0-B5C4-15385CC283D0Q50287459-8D371C1D-B334-49FF-8B45-5019DBC47F75Q50287469-2F33772A-4095-44B5-806F-0F681941A0DBQ50287476-E9E19BFF-D2CD-49C6-AEAB-EDD15FCE3437
P527
description
Macromolecular complex
@en
name
RPA heterotrimer
@en
type
label
RPA heterotrimer
@en
prefLabel
RPA heterotrimer
@en
P527
P2888
P3937
R-HSA-68462