Defective IKBKG (NEMO) destabilizes the association of IKBKA:IKBKB:IKBKG (via TLR) - Wikidata - awgldk - TriplyDB

Defective IKBKG (NEMO) destabilizes the association of IKBKA:IKBKB:IKBKG (via TLR)

Defective IKBKG (NEMO) destabilizes the association of IKBKA:IKBKB:IKBKG (via TLR)

http://www.wikidata.org/entity/Q50289677

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IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)

P527

Q45316718-06AF04EA-9883-42A5-98F8-A71C4B6A6E32

P527

Defective IKBKG (NEMO) destabilizes the association of IKBKA:IKBKB:IKBKG (via TLR)

http://www.wikidata.org/entity/Q50289677

description

An instance of the biological ...... KBKG (via TLR) in Homo sapiens

@en

biologisch proces

@nl

name

Defective IKBKG (NEMO) destabilizes the association of IKBKA:IKBKB:IKBKG (via TLR)

@en

type

label

Defective IKBKG (NEMO) destabilizes the association of IKBKA:IKBKB:IKBKG (via TLR)

@en

prefLabel

Defective IKBKG (NEMO) destabilizes the association of IKBKA:IKBKB:IKBKG (via TLR)

@en

P2860

Q50289677-31788C16-626A-4881-8449-1F107F8243C6

Q50289677-B51AF446-35F5-4DB6-9789-65161BA586F1

Q50289677-C4F399CF-BDB5-4BA1-8A00-29AD05A4698C

P2888

Q50289677-D48CBA81-A7FD-4513-8906-CE8358010D43

P31

Q50289677-4B913203-F9C7-4BF8-A341-C5563D16C621

P361

Q50289677-DF4000DB-41E5-490A-AD2B-2F2CAE05EB3D

P3937

Q50289677-637559C1-4C1D-462D-988D-438A455D74DA

P527

Q50289677-75F967BC-CA97-4CCB-AFCD-ED4A62C53669

Q50289677-A9CC6F1B-5363-43AA-86EC-07E963FE2073

Q50289677-B7FE6D97-DC16-4C34-853A-64D278F0F90F

P703

Q50289677-AC3B3DF5-B219-4CC7-A027-28A6851AC3E2

P2860

X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling

Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome.

Molecular analysis of the genetic defect in a large cohort of IP patients and identification of novel NEMO mutations interfering with NF-kappaB activation.

P2888

reactome:R-HSA-5262921

P31

biological process

P361

IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)

P3937

R-HSA-5262921

http://www.w3.org/2001/XMLSchema#string

P527

Component of inhibitor of nuclear factor kappa B kinase complex

TLR associated IKBKG variants

Inhibitor of nuclear factor kappa B kinase subunit beta

P703