SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex - Wikidata - awgldk - TriplyDB

SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex

SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex

http://www.wikidata.org/entity/Q50292528

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Interleukin-1 signaling

P527

Q55230679-8AF28795-C4A4-4C5A-99CA-DBD9099606B0

P527

SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex

http://www.wikidata.org/entity/Q50292528

description

An instance of the biological ...... o IKBA complex in Homo sapiens

@en

biologisch proces

@nl

name

SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex

@en

type

label

SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex

@en

prefLabel

SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex

@en

P2860

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Q50292528-FEF9A28A-730B-40C4-9D49-433EB93E4BAE

P2888

Q50292528-3924AF11-5DD9-4DD9-B1AA-7C7C3BB941D6

P31

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P361

Q50292528-6FCF9926-7BDE-49E9-AFD8-44DECE8E1F3B

P3937

Q50292528-3A1A18A5-7B82-4F96-BD7C-5B86E3528244

P527

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P703

Q50292528-4AC01326-EEFA-4D44-96E4-B49C1C0FA8BE

P2860

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

Molecular dissection of the interactions among IkappaBalpha, FWD1, and Skp1 required for ubiquitin-mediated proteolysis of IkappaBalpha.

Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.

P2888

reactome:R-HSA-209125

P31

biological process

P361

Interleukin-1 signaling

P3937

R-HSA-209125

http://www.w3.org/2001/XMLSchema#string

P527

BTRC:CUL1:RBX1:SKP1

NFKB1(1-433):RELA:p-S32;S36-NFKBIA

NFKB1(1-433):RELA:p-S32;S36-NFKBIA:BTRC:CUL1:RBX1:SKP1

P703