KCNJ11 tetramer:ABCC8 tetramer binds 4xATP; closing the channel - Wikidata - awgldk - TriplyDB

KCNJ11 tetramer:ABCC8 tetramer binds 4xATP; closing the channel

KCNJ11 tetramer:ABCC8 tetramer binds 4xATP; closing the channel

http://www.wikidata.org/entity/Q50294391

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Regulation of insulin secretion

P527

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P527

KCNJ11 tetramer:ABCC8 tetramer binds 4xATP; closing the channel

http://www.wikidata.org/entity/Q50294391

description

An instance of the biological ...... ng the channel in Homo sapiens

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biologisch proces

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name

KCNJ11 tetramer:ABCC8 tetramer binds 4xATP; closing the channel

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type

label

KCNJ11 tetramer:ABCC8 tetramer binds 4xATP; closing the channel

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prefLabel

KCNJ11 tetramer:ABCC8 tetramer binds 4xATP; closing the channel

@en

P2860

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Inwardly rectifying potassium channels: their structure, function, and physiological roles

The structure and function of the ATP-sensitive K+ channel in insulin-secreting pancreatic beta-cells.

Two regions of sulfonylurea receptor specify the spontaneous bursting and ATP inhibition of KATP channel isoforms.

Sulfonylurea receptor 1 and Kir6.2 expression in the novel human insulin-secreting cell line NES2Y.

Diverse roles of K(ATP) channels learned from Kir6.2 genetically engineered mice.

Triggering and amplifying pathways of regulation of insulin secretion by glucose.

A novel KCNJ11 mutation associated with congenital hyperinsulinism reduces the intrinsic open probability of beta-cell ATP-sensitive potassium channels

Characterization of voltage-dependent sodium and calcium channels in mouse pancreatic A- and B-cells.

Minireview: implication of mitochondria in insulin secretion and action.

Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes.

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reactome:R-HSA-265682

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biological process

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Regulation of insulin secretion

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R-HSA-265682

http://www.w3.org/2001/XMLSchema#string

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α-D-glucopyranose

PKA catalytic subunit

RAPGEF3:cAMP complex

RAPGEF4:cAMP Complex

KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer

Mg2+:ADP [cytosol]

KCNJ11:ATP tetramer:ABCC8 tetramer

adenosine triphosphate

P703