SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma.
about
Paradoxical role of SOX2 in gastric cancerTargeting Aggressive Cancer Stem Cells in GlioblastomaThe Oct4 protein: more than a magic stemness markerAldh1 Expression and Activity Increase During Tumor Evolution in Sarcoma Cancer Stem Cell Populations.Distinctive properties of metastasis-initiating cellsLong non-coding RNA SOX2OT: expression signature, splicing patterns, and emerging roles in pluripotency and tumorigenesisLgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumorsSox4 links tumor suppression to accelerated aging in mice by modulating stem cell activationThe Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell PhenotypeSOX2 is required to maintain cancer stem cells in ovarian cancer.Gene Expression Signature Differentiates Histology But Not Progression Status of Early-Stage NSCLC.Expression and functional regulation of stemness gene Lgr5 in esophageal squamous cell carcinoma.PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3.Hmga2 translocation induced in skin tumorigenesis.IGF-1 mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 CascadeSOX2 regulates acinar cell development in the salivary gland.Sox2, a marker for stem-like tumor cells in skin squamous cell carcinoma and hedgehog subgroup medulloblastomaThe Activation of the Sox2 RR2 Pluripotency Transcriptional Reporter in Human Breast Cancer Cell Lines is Dynamic and Labels Cells with Higher Tumorigenic Potential.Actin-like 6A predicts poor prognosis of hepatocellular carcinoma and promotes metastasis and epithelial-mesenchymal transition.Translation from unconventional 5' start sites drives tumour initiation.Pioneer transcription factors in cell reprogramming.Increased cycling cell numbers and stem cell associated proteins as potential biomarkers for high grade human papillomavirus+ve pre-neoplastic cervical disease.Prognostic significance of SOX2 in head and neck cancer: a meta-analysis.Oncogenesis and induced pluripotency - commonalities of signalling pathwaysPIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3β/CTNNB1 signaling pathway.Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways.CRISPR reveals a distal super-enhancer required for Sox2 expression in mouse embryonic stem cells.The pluripotency factor NANOG promotes the formation of squamous cell carcinomasDC120, a novel AKT inhibitor, preferentially suppresses nasopharyngeal carcinoma cancer stem-like cells by downregulating Sox2.TGF-β promotes heterogeneity and drug resistance in squamous cell carcinomaSilencing of phosphoglucose isomerase/autocrine motility factor decreases U87 human glioblastoma cell migration.The role of histone demethylase KDM4B in Myc signaling in neuroblastomaLimiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells.The converging roles of BRD4 and gene transcription in pluripotency and oncogenesisHigh sex determining region Y-box 2 (SOX2) expression correlates with absence of nodal metastasis in esophageal squamous cell carcinoma.Plumbagin suppresses epithelial to mesenchymal transition and stemness via inhibiting Nrf2-mediated signaling pathway in human tongue squamous cell carcinoma cells.Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis.Squamousness: Next-generation sequencing reveals shared molecular features across squamous tumor typesGene Perturbation Atlas (GPA): a single-gene perturbation repository for characterizing functional mechanisms of coding and non-coding genesRoles of sex-determining region Y-box 2 in cell pluripotency and tumor-related signaling pathways.
P2860
Q26749130-B099E612-2D1C-4087-86FF-C28E2DF37803Q26799983-5BAE53C4-8179-46B2-8854-694FF4481F7CQ26862078-EBD97552-2EFF-4538-A318-E5AB8C8B28ADQ27342050-77A225B8-541F-495A-8661-16DB6450F1ACQ28069801-35439DAA-7291-4A02-9561-AE51739D7C1AQ28082535-016FCBB3-6A3F-4A30-AFBF-F08176324CCAQ28817157-68506F90-B4C0-47AD-B9AB-A19C02766C7DQ28830512-B28A852A-B7D9-44CD-BA09-5FBDA893FAF5Q30276749-C511A456-D7BE-4569-8912-51E9F6ABD6D2Q33607622-57E61FC2-8878-496B-8392-6196E805A4BAQ33611881-D2082CCD-A74D-4B7A-9C99-2D0DDC572462Q33688716-415C6F5C-BDDC-4A9E-9F4A-7E167E316497Q33705644-916B46BA-59FD-4F1B-A182-0E97CD508898Q33728215-EA164871-0F6E-45E6-A7BA-BC15BBBA582BQ33789793-051FD391-B645-4734-A2DD-0138A898E423Q33874469-9EB2F8A6-01AE-466D-891D-A66DD074DBAFQ34332418-BCEDB6B7-F6AC-4250-B7C7-E9AAB5FD27AAQ34452128-01581169-A152-4D59-A3C8-78BC75A53733Q34506340-1A0BFEBF-60A2-48EA-8C30-14867C73BA4EQ34549017-C668E41C-0B3B-408E-9928-19D6800B9DE4Q34697693-17CD8624-E2E4-4EB8-A475-68B2BAE17D2CQ34756941-E04FE406-AC66-4B02-ADE3-8E75919A8EB6Q35017036-DB8ECA8C-AC95-4D66-9E6F-558A849F993FQ35066337-DF69C3DB-AA35-432D-B561-80B3E0F59421Q35165755-902F2AE5-8827-45B8-AD9D-7079DE8D6C12Q35261803-DECCC88B-CBEF-4AC2-94D5-BF8A016E83C5Q35500089-AC875485-AAB7-4C6C-A7E5-07238E98A6B2Q35623354-4A745A8E-1F63-4491-B983-803C5BED755AQ35740115-DC9C4D53-3A2E-4259-B519-C7F763023B7BQ35871985-D7A7AD0F-67F9-492B-8E0F-0DBEDA18B419Q35943863-17144374-78C8-4008-A67E-6CD0AC334571Q36014044-53B82D49-CC31-4651-93A8-46DFAEE7200CQ36030065-C90B7033-C828-4018-AB9D-30FB7BDEB8C1Q36081650-EB26F0A6-C9B3-4671-9130-8F379B2054FBQ36095229-1EDF09F7-87BA-4F36-A0D4-9CE1F84A6640Q36142170-C37A7836-4836-4A9C-8052-E90DE79ECDD7Q36156814-ACF56DF3-C747-406E-B479-4313FBFCA000Q36184728-02DE6EA7-C717-457D-B223-6B83063AB504Q36293551-CC3FD524-8B55-40AD-A473-D3FA3BB7A3C5Q36334636-8DBCE1B4-2831-44BD-8AA7-BCDE87942C90
P2860
SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh-hant
name
SOX2 controls tumour initiatio ...... ns in squamous-cell carcinoma.
@en
SOX2 controls tumour initiatio ...... ns in squamous-cell carcinoma.
@nl
type
label
SOX2 controls tumour initiatio ...... ns in squamous-cell carcinoma.
@en
SOX2 controls tumour initiatio ...... ns in squamous-cell carcinoma.
@nl
prefLabel
SOX2 controls tumour initiatio ...... ns in squamous-cell carcinoma.
@en
SOX2 controls tumour initiatio ...... ns in squamous-cell carcinoma.
@nl
P2093
P2860
P356
P1433
P1476
SOX2 controls tumour initiatio ...... ns in squamous-cell carcinoma.
@en
P2093
Amélie Caauwe
Benjamin Beck
Christine Dubois
Cédric Blanpain
Erwin Nkusi
Francois Fuks
Gaelle Lapouge
Gregory Driessens
Isabelle Salmon
Marie Le Mercier
P2860
P2888
P304
P356
10.1038/NATURE13305
P407
P577
2014-06-08T00:00:00Z