Increased expression of ribosome recycling factor is responsible for the enhanced protein synthesis during the late growth phase in an antibiotic-overproducing Streptomyces coelicolor ribosomal rpsL mutant.
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Dramatic activation of antibiotic production in Streptomyces coelicolor by cumulative drug resistance mutationsNovel two-component systems implied in antibiotic production in Streptomyces coelicolorOverexpression of ribosome recycling factor is responsible for improvement of nucleotide antibiotic-toyocamycin in Streptomyces diastatochromogenes 1628.Predictive Power of ETRE Polymorphism and Katg463 Mutation to INH-Resistance of M.tuberculosis.Mutations in rsmG, encoding a 16S rRNA methyltransferase, result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2)ScbR- and ScbR2-mediated signal transduction networks coordinate complex physiological responses in Streptomyces coelicolor.Activation of Antibiotic Production in Bacillus spp. by Cumulative Drug Resistance Mutations.Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolismAntibiotic biosynthetic pathways and pathway engineering--a growing research field in China.Molecular regulation of antibiotic biosynthesis in streptomyces.Novel links between antibiotic resistance and antibiotic productionActivation and products of the cryptic secondary metabolite biosynthetic gene clusters by rifampin resistance (rpoB) mutations in actinomycetes.Disruption of rimP-SC, encoding a ribosome assembly cofactor, markedly enhances the production of several antibiotics in Streptomyces coelicolor.A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction.Identification and characterization of a novel multidrug resistance operon, mdtRP (yusOP), of Bacillus subtilis.Antibiotic overproduction by rpsL and rsmG mutants of various actinomycetesStructural Insights into ribosome recycling factor interactions with the 70S ribosome.The mthA mutation conferring low-level resistance to streptomycin enhances antibiotic production in Bacillus subtilis by increasing the S-adenosylmethionine pool sizeStrain improvement in actinomycetes in the postgenomic era.New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters.Activating the expression of bacterial cryptic genes by rpoB mutations in RNA polymerase or by rare earth elements.Spontaneous and on point: Do spontaneous mutations used for laboratory experiments cause pleiotropic effects that might confound bacterial infection and evolution assays?Engineering microbial hosts for production of bacterial natural productsInsights into microbial cryptic gene activation and strain improvement: principle, application and technical aspects.Antibiotic dialogues: induction of silent biosynthetic gene clusters by exogenous small molecules.Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp.Repression of antibiotic production and sporulation in Streptomyces coelicolor by overexpression of a TetR family transcriptional regulator.An insight into the "-omics" based engineering of streptomycetes for secondary metabolite overproduction.AvaR2, a pseudo γ-butyrolactone receptor homologue from Streptomyces avermitilis, is a pleiotropic repressor of avermectin and avenolide biosynthesis and cell growth.Production of xylanase by an alkaline-tolerant marine-derived Streptomyces viridochromogenes strain and improvement by ribosome engineering.Overexpression of ribosome elongation factor G and recycling factor increases L-isoleucine production in Corynebacterium glutamicum.
P2860
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P2860
Increased expression of ribosome recycling factor is responsible for the enhanced protein synthesis during the late growth phase in an antibiotic-overproducing Streptomyces coelicolor ribosomal rpsL mutant.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Increased expression of riboso ...... licolor ribosomal rpsL mutant.
@en
Increased expression of riboso ...... licolor ribosomal rpsL mutant.
@nl
type
label
Increased expression of riboso ...... licolor ribosomal rpsL mutant.
@en
Increased expression of riboso ...... licolor ribosomal rpsL mutant.
@nl
prefLabel
Increased expression of riboso ...... licolor ribosomal rpsL mutant.
@en
Increased expression of riboso ...... licolor ribosomal rpsL mutant.
@nl
P2093
P2860
P1476
Increased expression of riboso ...... licolor ribosomal rpsL mutant.
@en
P2093
P2860
P304
P356
10.1111/J.1365-2958.2006.05285.X
P407
P577
2006-07-12T00:00:00Z