Targeted mutagenesis of the POU-domain gene Brn4/Pou3f4 causes developmental defects in the inner ear.
about
Diversity, phylogeny and expression patterns of Pou and Six homeodomain transcription factors in hydrozoan jellyfish Craspedacusta sowerbyiMüllerian inhibiting substance contributes to sex-linked biases in the brain and behaviorMolecular mechanisms of inner ear developmentMaking connections in the inner ear: recent insights into the development of spiral ganglion neurons and their connectivity with sensory hair cellsCooperative function of Tbx1 and Brn4 in the periotic mesenchyme is necessary for cochlea formationJxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of cortiPou3f4-mediated regulation of ephrin-b2 controls temporal bone development in the mouse.In vivo genetic ablation of the periotic mesoderm affects cell proliferation survival and differentiation in the cochlea.Tissue-specific roles of Tbx1 in the development of the outer, middle and inner ear, defective in 22q11DS patients.Specification of the mammalian cochlea is dependent on Sonic hedgehogDissecting the molecular basis of organ of Corti development: Where are we now?The influence of cochlear shape on low-frequency hearing.Cochlear progenitor number is controlled through mesenchymal FGF receptor signalingNovel domain-specific POU3F4 mutations are associated with X-linked deafness: examples from different populations.Cytoplasmic mislocalization of POU3F4 due to novel mutations leads to deafness in humans and mice.Conditional and inducible gene recombineering in the mouse inner earTympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells.Can you hear me now? Understanding vertebrate middle ear development.A mouse model with postnatal endolymphatic hydrops and hearing loss.Gene expression in cortical interneuron precursors is prescient of their mature function.Contribution of bone marrow hematopoietic stem cells to adult mouse inner ear: mesenchymal cells and fibrocytesOtic ablation of smoothened reveals direct and indirect requirements for Hedgehog signaling in inner ear development.Identification of putative retinoic acid target genes downstream of mesenchymal Tbx1 during inner ear developmentTbx1 and Brn4 regulate retinoic acid metabolic genes during cochlear morphogenesis.A claudin-9-based ion permeability barrier is essential for hearing.Characterization of new otic enhancers of the pou3f4 gene reveal distinct signaling pathway regulation and spatio-temporal patterns.Inner ear dysfunction in caspase-3 deficient miceMultiple enhancers located in a 1-Mb region upstream of POU3F4 promote expression during inner ear development and may be required for hearingThe role of Zic genes in inner ear development in the mouse: Exploring mutant mouse phenotypes.Application of physiological genomics to the study of hearing disorders.Chromodomain proteins in development: lessons from CHARGE syndrome.Effects of mouse utricle stromal tissues on hair cell induction from induced pluripotent stem cells.Extremely discrepant mutation spectrum of SLC26A4 between Chinese patients with isolated Mondini deformity and enlarged vestibular aqueductOtic mesenchyme cells regulate spiral ganglion axon fasciculation through a Pou3f4/EphA4 signaling pathwayPatterning of the mammalian cochlea.Myosin II regulates extension, growth and patterning in the mammalian cochlear duct.A genome-wide scan for signatures of selection in Chinese indigenous and commercial pig breeds.Octamer-binding transcription factors: genomics and functions.Analysis of Mll1 deficiency identifies neurogenic transcriptional modules and Brn4 as a factor for direct astrocyte-to-neuron reprogramming.Age-dependent gene expression in the inner ear of big brown bats (Eptesicus fuscus).
P2860
Q24631293-6096B657-4C50-4EB1-A762-2BFF91EE96F8Q24648962-05D9C81E-0B8E-4860-B1BC-6E65829E077FQ26865155-525DECFF-AB0B-4883-8362-66F136275226Q26991942-9B031010-CBE5-4C24-9599-6319AC36E32FQ28506318-BF716293-115D-47CC-A6A8-4236DA74BDE5Q28510448-E08D4539-9DD2-4B30-BFB1-8E80C528F8FDQ28543664-52F411B4-7189-41C3-931B-E25CAAC740D3Q28591405-07F6D58A-DAE0-4CEA-A97C-AE6F2B128119Q28592076-2568C966-A51D-4093-A375-57AE72339102Q28593205-BBDC3938-E5C6-406B-AFCA-DE0A40FF358DQ28744483-5978E6E1-DD02-452B-A4D4-F070A47933C6Q28755080-5D93B6B5-90E9-49A0-BBFC-DDD2D13C0FDBQ30411351-35EAC26F-E95A-4F83-90ED-77991CDBE2D8Q30412441-E7F70155-C9C1-4087-BABA-C288D8C49548Q30433617-9C5ED7D1-FF45-4E9A-846C-4839D8EEDD8FQ30444031-66F11318-73FB-452C-A422-236B9BD887A5Q30449308-A01BAAE2-FD8D-41A1-9790-42ECED6388A0Q30476155-99E66AD7-1AF7-4895-84BD-9DD489B9392BQ30481886-FA7E2873-C535-49AB-9FC7-ACB691F7CEFEQ30486244-2E0C6913-5A74-4EAC-B0CE-6647C95A37F1Q30493147-E350B300-9548-476C-BD1F-4723CBF3F477Q30503629-A2998E0B-0163-4822-9F9B-4797281191CEQ30505432-3CC1B0C7-070C-4627-9D87-9635A6F54CBBQ33455008-25E6534C-A547-4562-B31C-D97A3E6369C4Q33495556-788AA5BA-27F4-4B93-AF67-F5475EFDB499Q33786756-3DCC9CCC-D0FC-4B7D-80BC-F28D75921B6FQ34046269-0863F130-B88F-4065-A4C0-10E496409AE1Q34127314-435FA0B4-A7CF-4771-AA20-72B42FF071CBQ34389035-2AFAB302-D9EC-4CE6-8F98-EE28BC5F4072Q34786306-6CFFDBBA-054E-4C90-AF79-7B7E29401B1FQ34990736-92A6E4E3-E066-48F5-88EA-52467C518296Q35396960-B570061B-8C5A-4F8A-A05B-6AA2BFD3797CQ35477577-21D6E668-B5CE-48CE-B20A-5586E287AEFEQ35676073-B541944A-C2A3-437D-824E-2545A5E19ED9Q36208996-AC4ACDC1-64F5-4EA2-B99E-A236B8F5D8D2Q37200935-6D1A1AD0-70D1-4CF8-BF9B-46046B042ECFQ37502257-90FEA6F7-D48D-4D16-B37F-195C67D9D7F0Q38112991-384B64A3-4E14-467D-9DC8-58170F534BC4Q40283693-51103FDD-FC4D-4F59-99DE-DC4545A3239DQ44492142-1A121D0A-F859-4D0B-A44B-3786EE09D8EA
P2860
Targeted mutagenesis of the POU-domain gene Brn4/Pou3f4 causes developmental defects in the inner ear.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Targeted mutagenesis of the PO ...... ntal defects in the inner ear.
@en
Targeted mutagenesis of the PO ...... ntal defects in the inner ear.
@nl
type
label
Targeted mutagenesis of the PO ...... ntal defects in the inner ear.
@en
Targeted mutagenesis of the PO ...... ntal defects in the inner ear.
@nl
prefLabel
Targeted mutagenesis of the PO ...... ntal defects in the inner ear.
@en
Targeted mutagenesis of the PO ...... ntal defects in the inner ear.
@nl
P2093
P1476
Targeted mutagenesis of the PO ...... ntal defects in the inner ear.
@en
P2093
P304
P407
P577
1999-07-01T00:00:00Z