Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles. - Wikidata - awgldk - TriplyDB

Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles.

Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles.

http://www.wikidata.org/entity/Q50518352

about

Molecular and cell-based therapies for muscle degenerations: a road under construction The potential of sarcospan in adhesion complex replacement therapeutics for the treatment of muscular dystrophy Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy IRES-mediated translation of utrophin A is enhanced by glucocorticoid treatment in skeletal muscle cells Drug discovery for Duchenne muscular dystrophy via utrophin promoter activation screening Ets-2 repressor factor silences extrasynaptic utrophin by N-box mediated repression in skeletal muscle.High levels of sarcospan are well tolerated and act as a sarcolemmal stabilizer to address skeletal muscle and pulmonary dysfunction in DMD.Dystrophin delivery to muscles of mdx mice using lentiviral vectors leads to myogenic progenitor targeting and stable gene expression.Differential requirement for utrophin in the induced pluripotent stem cell correction of muscle versus fat in muscular dystrophy mice.Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration.Targeting artificial transcription factors to the utrophin A promoter: effects on dystrophic pathology and muscle function.Therapeutic approaches to muscular dystrophy.TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice.Whole body periodic acceleration is an effective therapy to ameliorate muscular dystrophy in mdx mice.Viral-mediated gene therapy for the muscular dystrophies: successes, limitations and recent advances Emerging drugs for Duchenne muscular dystrophy Inhibition of muscle fibrosis results in increases in both utrophin levels and the number of revertant myofibers in Duchenne muscular dystrophy.Sarcospan: a small protein with large potential for Duchenne muscular dystrophy Novel compounds for the treatment of Duchenne muscular dystrophy: emerging therapeutic agents Heregulin ameliorates the dystrophic phenotype in mdx mice.Preclinical studies for gene therapy of Duchenne muscular dystrophy.Progress in therapy for Duchenne muscular dystrophy.Update on the treatment of Duchenne muscular dystrophy.Duchenne muscular dystrophy drug discovery - the application of utrophin promoter activation screening.Gene-based therapies of neuromuscular disorders: an update and the pivotal role of patient organizations in their discovery and implementation.What has the mdx mouse model of Duchenne muscular dystrophy contributed to our understanding of this disease?Strength and muscle specificity of a compact promoter derived from the slow troponin I gene in the context of episomal (gutless adenovirus) and integrating (lentiviral) vectors.Overview of the Muscle Cytoskeleton.Upregulation of the creatine synthetic pathway in skeletal muscles of mature mdx mice.Thermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin.Functional improvement of dystrophic muscle by repression of utrophin: let-7c interaction.Targeting muscle stem cell intrinsic defects to treat Duchenne muscular dystrophy.Generation and Characterization of Transgenic Mice with the Full-length HumanDMDGene

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Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles.

http://www.wikidata.org/entity/Q50518352

description

1999 nî lūn-bûn

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1999年の論文

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年學術文章

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1999年學術文章

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name

Adenovirus-mediated utrophin g ...... henotype of mdx mouse muscles.

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Adenovirus-mediated utrophin g ...... henotype of mdx mouse muscles.

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type

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Adenovirus-mediated utrophin g ...... henotype of mdx mouse muscles.

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Adenovirus-mediated utrophin g ...... henotype of mdx mouse muscles.

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Adenovirus-mediated utrophin g ...... henotype of mdx mouse muscles.

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Adenovirus-mediated utrophin g ...... henotype of mdx mouse muscles.

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Adenovirus-mediated utrophin g ...... henotype of mdx mouse muscles.

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Davies KE

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Ebihara S

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Gilbert R

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Guibinga GH

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Kamen A

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