Ligand-induced conformational changes in cyclic nucleotide phosphodiesterases and cyclic nucleotide-dependent protein kinases.
about
Cyclic GMP phosphodiesterase-5: target of sildenafil.Binding of cGMP to the transducin-activated cGMP phosphodiesterase, PDE6, initiates a large conformational change involved in its deactivationCharacterization of conformational changes and protein-protein interactions of rod photoreceptor phosphodiesterase (PDE6).Molecular mechanisms that could contribute to prolonged effectiveness of PDE5 inhibitors to improve erectile function.Functional analysis of type 1alpha cGMP-dependent protein kinase using green fluorescent fusion proteins.Phosphorylation of isolated human phosphodiesterase-5 regulatory domain induces an apparent conformational change and increases cGMP binding affinity.Activation of cGMP-dependent protein kinase by protein kinase C.Activation by autophosphorylation or cGMP binding produces a similar apparent conformational change in cGMP-dependent protein kinase.
P2860
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P2860
Ligand-induced conformational changes in cyclic nucleotide phosphodiesterases and cyclic nucleotide-dependent protein kinases.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Ligand-induced conformational ...... ide-dependent protein kinases.
@en
Ligand-induced conformational ...... ide-dependent protein kinases.
@nl
type
label
Ligand-induced conformational ...... ide-dependent protein kinases.
@en
Ligand-induced conformational ...... ide-dependent protein kinases.
@nl
prefLabel
Ligand-induced conformational ...... ide-dependent protein kinases.
@en
Ligand-induced conformational ...... ide-dependent protein kinases.
@nl
P2093
P356
P1433
P1476
Ligand-induced conformational ...... ide-dependent protein kinases.
@en
P2093
Francis SH
P356
10.1006/METH.1997.0567
P577
1998-01-01T00:00:00Z