DNA methylation profiles define stem cell identity and reveal a tight embryonic-extraembryonic lineage boundary.
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Dnmt3b Prefers Germ Line Genes and Centromeric Regions: Lessons from the ICF Syndrome and Cancer and Implications for DiseasesRegulators associated with clinical outcomes revealed by DNA methylation data in breast cancer.Aberrant DNA methylation in ES cellsLineage-specific regulation of imprinted X inactivation in extraembryonic endoderm stem cellsADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cellsStable methylation at promoters distinguishes epiblast stem cells from embryonic stem cells and the in vivo epiblasts.In Vivo Chromatin Targets of the Transcription Factor Yin Yang 2 in Trophoblast Stem Cells.Characterization of Histone Modifications Associated with Inactive X-Chromosome in Trophoblast Stem Cells, eXtra-Embryonic Endoderm Cells and in In Vitro Derived Undifferentiated and Differentiated Epiblast Like Stem CellsMapping global changes in nuclear cytosine base modifications in the early mouse embryo.DNA methyltransferases and TETs in the regulation of differentiation and invasiveness of extra-villous trophoblasts.Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naïve pluripotency by complementary mechanisms.Derivation and maintenance of murine trophoblast stem cells under defined conditions.Derivation of extraembryonic endoderm stem (XEN) cells from mouse embryos and embryonic stem cells.PGC7 suppresses TET3 for protecting DNA methylation.Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation.Analysis of Ferrous on Ten-Eleven Translocation Activity and Epigenetic Modifications of Early Mouse Embryos by Fluorescence Microscopy.Epigenesis and plasticity of mouse trophoblast stem cells.Cdx2 efficiently induces trophoblast stem-like cells in naïve, but not primed, pluripotent stem cellsComparative FAIRE-seq analysis reveals distinguishing features of the chromatin structure of ground state- and primed-pluripotent cells.DNA methylation is dispensable for changes in global chromatin architecture but required for chromocentre formation in early stem cell differentiation.Plet1 is an epigenetically regulated cell surface protein that provides essential cues to direct trophoblast stem cell differentiation.Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast.XEN and the Art of Stem Cell Maintenance: Molecular Mechanisms Maintaining Cell Fate and Self-Renewal in Extraembryonic Endoderm Stem (XEN) Cell Lines.Spontaneous reactivation of clusters of X-linked genes is associated with the plasticity of X-inactivation in mouse trophoblast stem cells.A Critical Role of TET1/2 Proteins in Cell-Cycle Progression of Trophoblast Stem Cells.
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DNA methylation profiles define stem cell identity and reveal a tight embryonic-extraembryonic lineage boundary.
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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DNA methylation profiles defin ...... traembryonic lineage boundary.
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DNA methylation profiles defin ...... traembryonic lineage boundary.
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DNA methylation profiles defin ...... traembryonic lineage boundary.
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DNA methylation profiles defin ...... traembryonic lineage boundary.
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DNA methylation profiles defin ...... traembryonic lineage boundary.
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DNA methylation profiles defin ...... traembryonic lineage boundary.
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DNA methylation profiles defin ...... traembryonic lineage boundary.
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David Oxley
Simon Andrews
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P304
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10.1002/STEM.1249
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2012-12-01T00:00:00Z