about
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Negative regulation by PD-L1 during drug-specific priming of IL-22-secreting T cells and the influence of PD-1 on effector T cell function.Are drug metabolites able to cause T-cell-mediated hypersensitivity reactions?New Approaches to Investigate Drug-Induced Hypersensitivity.In Vitro Priming of Naı̈ve T-cells with p-Phenylenediamine and Bandrowski's Base.Characterization of primary human T-cell responses to p-phenylenediamine and Bandrowski's base.The Effect of Inhibitory Signals on the Priming of Drug Hapten-Specific T Cells That Express Distinct Vβ Receptors.Identification of drug- and drug-metabolite immune responses originating from both naive and memory T cells.Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury.7th Drug hypersensitivity meeting: part two.
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Andrew Gibson
@ast
Andrew Gibson
@en
Andrew Gibson
@es
Andrew Gibson
@nl
Andrew Gibson
@sl
type
label
Andrew Gibson
@ast
Andrew Gibson
@en
Andrew Gibson
@es
Andrew Gibson
@nl
Andrew Gibson
@sl
prefLabel
Andrew Gibson
@ast
Andrew Gibson
@en
Andrew Gibson
@es
Andrew Gibson
@nl
Andrew Gibson
@sl
P106
P21
P31
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0000-0001-9653-3298