A methylation-phosphorylation switch determines Sox2 stability and function in ESC maintenance or differentiation.
about
SIRT3 inhibits prostate cancer by destabilizing oncoprotein c-MYC through regulation of the PI3K/Akt pathway.Targeting SOX2 as a Therapeutic Strategy in GlioblastomaPalmitoylated SCP1 is targeted to the plasma membrane and negatively regulates angiogenesis.MOF as an evolutionarily conserved histone crotonyltransferase and transcriptional activation by histone acetyltransferase-deficient and crotonyltransferase-competent CBP/p300.IGF-1 mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 CascadeSET7/9 methylation of the pluripotency factor LIN28A is a nucleolar localization mechanism that blocks let-7 biogenesis in human ESCsRepression of hypoxia-inducible factor α signaling by Set7-mediated methylation.A CDC20-APC/SOX2 Signaling Axis Regulates Human Glioblastoma Stem-like Cells.Novel Function of Lysine Methyltransferase G9a in the Regulation of Sox2 Protein StabilitySETD7 Regulates the Differentiation of Human Embryonic Stem Cells.Cyclin-dependent kinase-mediated Sox2 phosphorylation enhances the ability of Sox2 to establish the pluripotent stateSOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis.Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.Molecular and functional interactions between AKT and SOX2 in breast carcinomaSOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cellsMitotic phosphorylation of SOX2 mediated by Aurora kinase A is critical for the stem-cell like cell maintenance in PA-1 cells.Ube2s regulates Sox2 stability and mouse ES cell maintenanceSet7 mediated interactions regulate transcriptional networks in embryonic stem cells.The deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog.IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development.Post-translational control of transcription factors: methylation ranks highly.The dark side of SOX2: cancer - a comprehensive overview.Carvedilol-responsive microRNAs, miR-199a-3p and -214 protect cardiomyocytes from simulated ischemia-reperfusion injury.Galectin-3 modulates the EGFR signalling-mediated regulation of Sox2 expression via c-Myc in lung cancer.Lysine Methyltransferase SETD7 (SET7/9) Regulates ROS Signaling through mitochondria and NFE2L2/ARE pathwaySox2: regulation of expression and contribution to brain tumors.Targeting Deubiquitinating Enzymes in Glioblastoma Multiforme: Expectations and Challenges.Emerging role of DUBs in tumor metastasis and apoptosis: Therapeutic implication.Ubiquitin-Dependent Regulation of Stem Cell Biology.Novel AKT phosphorylation sites identified in the pluripotency factors OCT4, SOX2 and KLF4H3K4 Methyltransferase Set1a Is A Key Oct4 Coactivator Essential for Generation of Oct4 Positive Inner Cell Mass.Structure of the HECT domain of human WWP2.Cyclin-Dependent Kinase-Dependent Phosphorylation of Sox2 at Serine 39 Regulates Neurogenesis.X-chromosome dosage as a modulator of pluripotency, signalling and differentiation?Proteasomes in Protein Homeostasis of Pluripotent Stem Cells.Critical roles of protein methyltransferases and demethylases in the regulation of embryonic stem cell fate.LincRNA-1614 coordinates Sox2/PRC2-mediated repression of developmental genes in pluripotency maintenance.Phosphorylation of Sox2 at Threonine 116 is a Potential Marker to Identify a Subset of Breast Cancer Cells with High Tumorigenecity and Stem-Like Features.Targeting posttranslational modifications of RIOK1 inhibits the progression of colorectal and gastric cancers.RIT1 GTPase Regulates Sox2 Transcriptional Activity and Hippocampal Neurogenesis.
P2860
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P2860
A methylation-phosphorylation switch determines Sox2 stability and function in ESC maintenance or differentiation.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh-hant
name
A methylation-phosphorylation ...... aintenance or differentiation.
@en
A methylation-phosphorylation ...... aintenance or differentiation.
@nl
type
label
A methylation-phosphorylation ...... aintenance or differentiation.
@en
A methylation-phosphorylation ...... aintenance or differentiation.
@nl
prefLabel
A methylation-phosphorylation ...... aintenance or differentiation.
@en
A methylation-phosphorylation ...... aintenance or differentiation.
@nl
P2093
P1433
P1476
A methylation-phosphorylation ...... aintenance or differentiation.
@en
P2093
James X Du
Jiemin Wong
Ling Zhang
Xueling Jin
P304
P356
10.1016/J.MOLCEL.2014.06.018
P50
P577
2014-07-17T00:00:00Z