A human anti-D monoclonal antibody selected for enhanced FcgammaRIII engagement clears RhD+ autologous red cells in human volunteers as efficiently as polyclonal anti-D antibodies.

A human anti-D monoclonal antibody selected for enhanced FcgammaRIII engagement clears RhD+ autologous red cells in human volunteers as efficiently as polyclonal anti-D antibodies.

Item
http://www.wikidata.org/entity/Q50659071
Anti-RhD immunoglobulin in the treatment of immune thrombocytopeniaRozrolimupab, a first-in-class recombinant monoclonal antibody product for primary immune thrombocytopaenia.The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells.Clearance of human IgG1-sensitised red blood cells in vivo in humans relates to the in vitro properties of antibodies from alternative cell lines.The emerging importance of α-L-fucose in human breast cancer: a review.Prophylactic anti-D preparations display variable decreases in Fc-fucosylation of anti-D.Giving monoclonal antibodies to healthy volunteers in phase 1 trials: is it safe?Lessons learnt from many years of experience using anti-D in humans for prevention of RhD immunization and haemolytic disease of the fetus and newborn.Anti-rhesus D prophylaxis in pregnant women is based on sialylated IgG antibodiesCombined glyco- and protein-Fc engineering simultaneously enhance cytotoxicity and half-life of a therapeutic antibody.Selection of IgG Variants with Increased FcRn Binding Using Random and Directed Mutagenesis: Impact on Effector Functions.5th European Antibody Congress 2009: November 30–December 2, 2009, Geneva, Switzerland.Anti-KEL sera prevents alloimmunization to transfused KEL RBCs in a murine model.Improved in vitro and in vivo activity against CD303-expressing targets of the chimeric 122A2 antibody selected for specific glycosylation pattern.
P2860

A human anti-D monoclonal antibody selected for enhanced FcgammaRIII engagement clears RhD+ autologous red cells in human volunteers as efficiently as polyclonal anti-D antibodies.

Item
http://www.wikidata.org/entity/Q50659071
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
A human anti-D monoclonal anti ...... polyclonal anti-D antibodies.
@en
A human anti-D monoclonal anti ...... polyclonal anti-D antibodies.
@nl
type
label
A human anti-D monoclonal anti ...... polyclonal anti-D antibodies.
@en
A human anti-D monoclonal anti ...... polyclonal anti-D antibodies.
@nl
prefLabel
A human anti-D monoclonal anti ...... polyclonal anti-D antibodies.
@en
A human anti-D monoclonal anti ...... polyclonal anti-D antibodies.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P356
P1433
P1476
A human anti-D monoclonal anti ...... polyclonal anti-D antibodies.
@en
P2093
P2860
P304
P31
P356
10.1111/J.1365-2141.2008.06985.X
P407
P433
P478
P577
P5875
P698
P921