Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia.

Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia.

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http://www.wikidata.org/entity/Q50662692
Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugsCalling in SYK: SYK's dual role as a tumor promoter and tumor suppressor in cancer.A PREVIOUSLY UNKNOWN UNIQUE CHALLENGE FOR INHIBITORS OF SYK ATP-BINDING SITE: ROLE OF SYK AS A CELL CYCLE CHECKPOINT REGULATORRAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals.Novel methods and approaches to acute lymphoblastic leukemia drug discovery.Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition.Syk inhibitors in clinical development for hematological malignancies.Dynamic pre-BCR homodimers fine-tune autonomous survival signals in B cell precursor acute lymphoblastic leukemia.Suppression of Spleen Tyrosine Kinase (Syk) by Histone Deacetylation Promotes, Whereas BAY61-3606, a Synthetic Syk Inhibitor Abrogates Colonocyte Apoptosis by ERK Activation.Anticancer drugs: Hitting SYK in B-ALL leukaemia.Crystal Structures of Spleen Tyrosine Kinase in Complex with Two Novel 4-Aminopyrido[4,3-d] Pyrimidine Derivative Inhibitors.Identification of spleen tyrosine kinase as a potential therapeutic target for esophageal squamous cell carcinoma using reverse phase protein arrays.
P2860

Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia.

Item
http://www.wikidata.org/entity/Q50662692
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh-hant
name
Therapeutic potential of splee ...... acute lymphoblastic leukemia.
@en
Therapeutic potential of splee ...... acute lymphoblastic leukemia.
@nl
type
label
Therapeutic potential of splee ...... acute lymphoblastic leukemia.
@en
Therapeutic potential of splee ...... acute lymphoblastic leukemia.
@nl
prefLabel
Therapeutic potential of splee ...... acute lymphoblastic leukemia.
@en
Therapeutic potential of splee ...... acute lymphoblastic leukemia.
@nl
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P2860
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P5875
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Therapeutic potential of splee ...... l acute lymphoblastic leukemia
@en
P2093
P2860
P304
P31
P356
10.1126/SCITRANSLMED.3008661
P407
P433
P478
P50
P577
P5875
P698
P921