Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.
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Shotgun lipidomics reveals the temporally dependent, highly diversified cardiolipin profile in the mammalian brain: temporally coordinated postnatal diversification of cardiolipin molecular species with neuronal remodelingFormation of molecular species of mitochondrial cardiolipin. 1. A novel transacylation mechanism to shuttle fatty acids between sn-1 and sn-2 positions of multiple phospholipid speciesMammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functionsPhospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionLpx1p is a peroxisomal lipase required for normal peroxisome morphology.Multi-dimensional mass spectrometry-based shotgun lipidomics and novel strategies for lipidomic analysesCalcium-independent phospholipase A2 in rabbit ventricular myocytesGroup VIA Ca2+-independent phospholipase A2 (iPLA2beta) and its role in beta-cell programmed cell death.Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet.Dysregulation of cardiolipin biosynthesis in pediatric heart failure.Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotypeLoss of function variants in human PNPLA8 encoding calcium-independent phospholipase A2 γ recapitulate the mitochondriopathy of the homologous null mouseThe metabolic serine hydrolases and their functions in mammalian physiology and disease.Activation of mitochondrial calcium-independent phospholipase A2γ (iPLA2γ) by divalent cations mediating arachidonate release and production of downstream eicosanoids.Calcium-independent phospholipases A2 and their roles in biological processes and diseases.CD36 protein influences myocardial Ca2+ homeostasis and phospholipid metabolism: conduction anomalies in CD36-deficient mice during fasting.Group VIB Phospholipase A(2) promotes proliferation of INS-1 insulinoma cells and attenuates lipid peroxidation and apoptosis induced by inflammatory cytokines and oxidant agentsCardiolipin synthesis for the assembly of bacterial and mitochondrial membranes.Tryptase activates calcium-independent phospholipase A2 and releases PGE2 in airway epithelial cells.Eicosanoid signalling pathways in the heart.Calcium-independent phospholipases in the heart: mediators of cellular signaling, bioenergetics, and ischemia-induced electrophysiologic dysfunctionGenetic ablation of calcium-independent phospholipase A2{gamma} leads to alterations in hippocampal cardiolipin content and molecular species distribution, mitochondrial degeneration, autophagy, and cognitive dysfunction.The phospholipase iPLA2γ is a major mediator releasing oxidized aliphatic chains from cardiolipin, integrating mitochondrial bioenergetics and signaling.Cardiac Myocyte-specific Knock-out of Calcium-independent Phospholipase A2γ (iPLA2γ) Decreases Oxidized Fatty Acids during Ischemia/Reperfusion and Reduces Infarct Size.Lipid droplet biogenesis induced by stress involves triacylglycerol synthesis that depends on group VIA phospholipase A2.Rate of acyl migration in lysophosphatidylcholine (LPC) is dependent upon the nature of the acyl group. Greater stability of sn-2 docosahexaenoyl LPC compared to the more saturated LPC species.Lipid Droplets in Cancer: Guardians of Fat in a Stressful World
P2860
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P2860
Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.
description
2007 nî lūn-bûn
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2007年の論文
@ja
2007年学术文章
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2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
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2007年學術文章
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2007年學術文章
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name
Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.
@en
Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.
@nl
type
label
Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.
@en
Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.
@nl
prefLabel
Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.
@en
Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.
@nl
P2093
P2860
P921
P356
P1476
Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.
@en
P2093
Christopher M Jenkins
Dana R Abendschein
David J Mancuso
Harold F Sims
Jeffrey E Saffitz
Jingyue Yang
John J Lehman
Karen Green
Nandakumar Sambandam
P2860
P304
P356
10.1074/JBC.M607307200
P407
P577
2007-01-09T00:00:00Z