Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase.
about
B cells take the front seat: dysregulated B cell signals orchestrate loss of tolerance and autoantibody productionTargeting the tyrosine kinase signalling pathways for treatment of immune-mediated glomerulonephritis: from bench to bedside and beyond.Activation-induced necroptosis contributes to B-cell lymphopenia in active systemic lupus erythematosus.The role of tyrosine kinases in systemic lupus erythematosus and their potential as therapeutic targets.Therapeutic Blockade of Immune Complex-Mediated Glomerulonephritis by Highly Selective Inhibition of Bruton's Tyrosine Kinase.Targeting spleen tyrosine kinase-Bruton's tyrosine kinase axis for immunologically mediated glomerulonephritis.Intrinsic autoimmune capacities of hematopoietic cells from female New Zealand hybrid mice.Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.Ibrutinib and novel BTK inhibitors in clinical development.Molecular abnormalities of the B cell in systemic lupus erythematosus are candidates for functional inhibition treatments.BTK Signaling in B Cell Differentiation and Autoimmunity.Lupus nephritis and B-cell targeting therapy.Targeting plasma cells: are we any closer to a panacea for diseases of antibody-secreting cells?The role of Bruton's tyrosine kinase in autoimmunity and implications for therapy.Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease.An update on lupus animal models.(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fcγ receptor signaling.HM71224, a selective Bruton's tyrosine kinase inhibitor, attenuates the development of murine lupus.Which B-cell subset should we target in lupus?Highly selective inhibition of Bruton's tyrosine kinase attenuates skin and brain disease in murine lupus.Bruton's Tyrosine Kinase, a Component of B Cell Signaling Pathways, Has Multiple Roles in the Pathogenesis of Lupus.Increased expression of Bruton's tyrosine kinase in peripheral blood is associated with lupus nephritis.Enhanced Expression of Bruton's Tyrosine Kinase in B Cells Drives Systemic Autoimmunity by Disrupting T Cell Homeostasis.Lyn, Lupus, and (B) Lymphocytes, a Lesson on the Critical Balance of Kinase Signaling in Immunity.CircIBTK inhibits DNA demethylation and activation of AKT signaling pathway via miR-29b in peripheral blood mononuclear cells in systemic lupus erythematosus.
P2860
Q26996644-0F4245DD-1861-4C38-AD84-D5E12D6D150CQ33620537-8D573A0B-AF6D-402B-9B39-E1F3AF84392CQ34476578-E6A9FD16-F55A-455B-B06F-0B28C2ED608DQ34597949-D1A9B4FA-0239-4D95-8295-FB5280B0DAABQ36914803-57F5BEF0-E25A-43CD-8750-9AE02E2D9EA3Q37700471-4BA70F87-F0C3-4A9D-BF9C-91100E1BA556Q37722598-E4A0A511-0920-4424-891D-DE0F5FF36F20Q37730801-8CCBA75D-6ED6-453B-AEF1-29C946C72F7CQ38130010-AAA39DA9-5026-434B-8504-A7A063161D6EQ38192725-67F3B05F-CFE5-4D3A-9F89-FC01796D2F5BQ38581000-A8734BA6-33F1-40AB-BAFE-D1C0C399F4EEQ38643755-E02F6303-AAD1-48EE-8FB8-E45BC03E7D28Q38728585-2C5AB85D-78F7-4969-AF22-20D7E95C94FEQ38728631-41B266FD-6F57-46C4-909C-BF15BDDEF33CQ38988830-D4E6A061-FB59-41C0-841C-186CFF5C8D93Q39326265-439009D6-0AEA-4E26-86A2-09B4F76B993FQ40054103-872F20C1-13A7-4C33-8BFF-D8019AA38D88Q41670053-4571A621-2CE9-4049-86DE-D3B7D62E3323Q46005728-32887437-2CBD-45BD-AC97-7313049D9304Q47647317-024E6F9E-DBF8-4C26-9C52-9612B8AF9B15Q50066279-9B3631C8-0539-495C-BD37-DE1D52094775Q50945737-CA6605D1-22D9-4B3E-A67F-FF41C0747D20Q52671903-8D7046BE-520A-41FC-974F-02E432EE6148Q52726230-0AD90CA9-2FBE-441D-B6A2-7C9B88920C97Q55476959-A22B611A-BF04-47F2-89FF-A259C45D30B6
P2860
Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Suppression of glomerulonephri ...... r of Bruton's tyrosine kinase.
@en
Suppression of glomerulonephri ...... r of Bruton's tyrosine kinase.
@nl
type
label
Suppression of glomerulonephri ...... r of Bruton's tyrosine kinase.
@en
Suppression of glomerulonephri ...... r of Bruton's tyrosine kinase.
@nl
prefLabel
Suppression of glomerulonephri ...... r of Bruton's tyrosine kinase.
@en
Suppression of glomerulonephri ...... r of Bruton's tyrosine kinase.
@nl
P2093
P2860
P356
P1476
Suppression of glomerulonephri ...... or of Bruton's tyrosine kinase
@en
P2093
Alka Patel
Holly Hilton
Jacob LaStant
John Woods
Julia Ayala
Julie DeMartino
Julie Hang
Kai-Yeung Lau
Mario Giron
P2860
P304
P356
10.1002/ART.38047
P577
2013-09-01T00:00:00Z