The role of erk1 and erk2 in multiple stages of T cell development.
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Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signalingBerberine differentially modulates the activities of ERK, p38 MAPK, and JNK to suppress Th17 and Th1 T cell differentiation in type 1 diabetic miceThemis controls thymocyte selection through regulation of T cell antigen receptor-mediated signalingRasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responsesRedundancy in the World of MAP Kinases: All for OneERK1 and ERK2 Map Kinases: Specific Roles or Functional Redundancy?Lower Affinity T Cells are Critical Components and Active Participants of the Immune ResponseB-Raf-mediated signaling pathway regulates T cell developmentGasp, a Grb2-associating protein, is critical for positive selection of thymocytesDUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibilityB-Raf is required for positive selection and survival of DP cells, but not for negative selection of SP cellsPresenilins regulate alphabeta T cell development by modulating TCR signalingRegulation of T cell development by the deubiquitinating enzyme CYLDThe essential function for serum response factor in T-cell development reflects its specific coupling to extracellular signal-regulated kinase signalingBCL11B is required for positive selection and survival of double-positive thymocytesGenetic analysis of Ras signalling pathways in cell proliferation, migration and survival.Lck SH3 domain function is required for T-cell receptor signals regulating thymocyte development.Coordinated regulation of transcription factor Bcl11b activity in thymocytes by the mitogen-activated protein kinase (MAPK) pathways and protein sumoylation.CCAAT/enhancer-binding proteins (C/EBP)-α and -β are essential for ovulation, luteinization, and the expression of key target genesShcA mediates the dominant pathway to extracellular signal-regulated kinase activation during early thymic developmentERK activation causes epilepsy by stimulating NMDA receptor activityRegulation of RasGRP1 function in T cell development and activation by its unique tail domain.Ubc9 Is Required for Positive Selection and Late-Stage Maturation of Thymocytes.Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.Extracellular Signal-Regulated Kinase Signaling in CD4-Expressing Cells Inhibits Osteochondromas.Prosurvival and proapoptotic functions of ERK1/2 activation in murine thymocytes in vitro.Thymic nurse cells exhibit epithelial progenitor phenotype and create unique extra-cytoplasmic membrane space for thymocyte selectionCutting edge: Extracellular signal-related kinase is not required for negative selection of developing T cells.MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility.The Erk2 MAPK regulates CD8 T cell proliferation and survival.Growth arrest signaling of the Raf/MEK/ERK pathway in cancer.Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferationThe death effector domain protein PEA-15 negatively regulates T-cell receptor signaling.The catalytic activity of the mitogen-activated protein kinase extracellular signal-regulated kinase 3 is required to sustain CD4+ CD8+ thymocyte survival.PKCtheta is necessary for efficient activation of NFkappaB, NFAT, and AP-1 during positive selection of thymocytes.Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection.Central B-cell tolerance: where selection begins.Kinase suppressor of Ras 1 is required for full ERK activation in thymocytes but not for thymocyte selection.Life and death in the thymus--cell death signaling during T cell development.Single-cell mass cytometry of TCR signaling: amplification of small initial differences results in low ERK activation in NOD mice
P2860
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P2860
The role of erk1 and erk2 in multiple stages of T cell development.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
The role of erk1 and erk2 in multiple stages of T cell development.
@en
The role of erk1 and erk2 in multiple stages of T cell development.
@nl
type
label
The role of erk1 and erk2 in multiple stages of T cell development.
@en
The role of erk1 and erk2 in multiple stages of T cell development.
@nl
prefLabel
The role of erk1 and erk2 in multiple stages of T cell development.
@en
The role of erk1 and erk2 in multiple stages of T cell development.
@nl
P2093
P1433
P1476
The role of erk1 and erk2 in multiple stages of T cell development.
@en
P2093
April M Fischer
Carol D Katayama
Giles Pagès
Stephen M Hedrick
P304
P356
10.1016/J.IMMUNI.2005.08.013
P407
P577
2005-10-01T00:00:00Z