Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo.
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Discovery of monocarbonyl curcumin-BTP hybrids as STAT3 inhibitors for drug-sensitive and drug-resistant breast cancer therapy.IL-6R/STAT3/miR-204 feedback loop contributes to cisplatin resistance of epithelial ovarian cancer cells.Inhibition of Pax2 Transcription Activation with a Small Molecule that Targets the DNA Binding Domain.Proteasome Inhibitor YSY01A Enhances Cisplatin Cytotoxicity in Cisplatin-Resistant Human Ovarian Cancer Cells.Correlation between p-STAT3 overexpression and prognosis in lung cancer: A systematic review and meta-analysisSignal transducer and activator of transcription 3 as a therapeutic target for cancer and the tumor microenvironment.Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors.Proteasome Inhibitor YSY01A Abrogates Constitutive STAT3 Signaling via Down-regulation of Gp130 and JAK2 in Human A549 Lung Cancer Cells.The effects of signal transducer and activator of transcription three mutations on human platelets.Drugging the "undruggable" DNA-binding domain of STAT3MMPP Attenuates Non-Small Cell Lung Cancer Growth by Inhibiting the STAT3 DNA-Binding Activity via Direct Binding to the STAT3 DNA-Binding Domain.Targeting the Bacterial Orisome in the Search for New Antibiotics.APC loss in breast cancer leads to doxorubicin resistance via STAT3 activation.Novel synthetic bisindolylmaleimide alkaloids inhibit STAT3 activation by binding to the SH2 domain and suppress breast xenograft tumor growth.The role of STAT3 in leading the crosstalk between human cancers and the immune system.14-3-3σ Contributes to Radioresistance By Regulating DNA Repair and Cell Cycle via PARP1 and CHK2.eIF3 Regulation of Protein Synthesis, Tumorigenesis, and Therapeutic Response.A new synthetic derivative of cryptotanshinone KYZ3 as STAT3 inhibitor for triple-negative breast cancer therapyA high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3)Lycorine Displays Potent Antitumor Efficacy in Colon Carcinoma by Targeting STAT3
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P2860
Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
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2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
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2015年學術文章
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2015年學術文章
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name
Small-molecule inhibitors targ ...... arget gene expression in vivo.
@en
Small-molecule inhibitors targ ...... arget gene expression in vivo.
@nl
type
label
Small-molecule inhibitors targ ...... arget gene expression in vivo.
@en
Small-molecule inhibitors targ ...... arget gene expression in vivo.
@nl
prefLabel
Small-molecule inhibitors targ ...... arget gene expression in vivo.
@en
Small-molecule inhibitors targ ...... arget gene expression in vivo.
@nl
P2093
P2860
P356
P1433
P1476
Small-molecule inhibitors targ ...... arget gene expression in vivo.
@en
P2093
G Sandusky
H E Broxmeyer
P2860
P2888
P304
P356
10.1038/ONC.2015.215
P407
P577
2015-06-15T00:00:00Z