Improved antimicrobial peptides based on acyl-lysine oligomers.
about
In Vivo, In Vitro, and In Silico Characterization of Peptoids as Antimicrobial AgentsCharacterization of a potent antimicrobial lipopeptide via coarse-grained molecular dynamics.Synthesis, antibacterial activity and mode of action of novel linoleic acid-dipeptide-spermidine conjugates.Simulating the mechanism of antimicrobial lipopeptides with all-atom molecular dynamics.A miniature mimic of host defense peptides with systemic antibacterial efficacy.Suppression of soft tissue sarcoma growth by a host defense-like lytic peptide.Role of the conformational rigidity in the design of biomimetic antimicrobial compounds.Guanidino groups greatly enhance the action of antimicrobial peptidomimetics against bacterial cytoplasmic membranesActin enables the antimicrobial action of LL-37 peptide in the presence of microbial proteasesUnderlying mechanism of in vivo and in vitro activity of C-terminal-amidated thanatin against clinical isolates of extended-spectrum beta-lactamase-producing Escherichia coliAcinetobacter baumannii: emergence of a successful pathogenR-thanatin inhibits growth and biofilm formation of methicillin-resistant Staphylococcus epidermidis in vivo and in vitro.Adaptive evolution of Escherichia coli to an α-peptide/β-peptoid peptidomimetic induces stable resistance.Antibacterial studies of cationic polymers with alternating, random, and uniform backbones.Antiplasmodial properties of acyl-lysyl oligomers in culture and animal models of malaria.Will new generations of modified antimicrobial peptides improve their potential as pharmaceuticals?The role of antimicrobial peptides in preventing multidrug-resistant bacterial infections and biofilm formation.Ultrashort peptide bioconjugates are exclusively antifungal agents and synergize with cyclodextrin and amphotericin B.The oligo-acyl lysyl antimicrobial peptide C₁₂K-2β₁₂ exhibits a dual mechanism of action and demonstrates strong in vivo efficacy against Helicobacter pylori.Membrane-Active Small Molecules: Designs Inspired by Antimicrobial Peptides.In vivo biodistribution and small animal PET of (64)Cu-labeled antimicrobial peptoids.Amino-terminated generation 2 poly(amidoamine) dendrimer as a potential broad-spectrum, nonresistance-inducing antibacterial agent.Calcium and Magnesium Ions Are Membrane-Active against Stationary-Phase Staphylococcus aureus with High Specificity.Synthetic mimic of antimicrobial peptide with nonmembrane-disrupting antibacterial propertiesDe novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers.Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfishAntibacterial properties and mode of action of a short acyl-lysyl oligomer.De novo designed synthetic mimics of antimicrobial peptides.Structure, membrane orientation, mechanism, and function of pexiganan--a highly potent antimicrobial peptide designed from magainin.Comparison of facially amphiphilic versus segregated monomers in the design of antibacterial copolymers.In vitro antibacterial activity of acyl-lysyl oligomers against Helicobacter pylori.Cationic amphiphiles, a new generation of antimicrobials inspired by the natural antimicrobial peptide scaffoldBeta-peptoid "foldamers"--why the additional methylene unit?Bacterial membrane lipids in the action of antimicrobial agents.Short native antimicrobial peptides and engineered ultrashort lipopeptides: similarities and differences in cell specificities and modes of action.Beyond natural antimicrobial peptides: multimeric peptides and other peptidomimetic approaches.Dual-acting hybrid antibiotics: a promising strategy to combat bacterial resistance.Revisiting eukaryotic anti-infective biotherapeutics.Cationic antimicrobial polymers and their assemblies.Combating multidrug-resistant bacteria: current strategies for the discovery of novel antibacterials.
P2860
Q28553205-D6EA97BC-591F-473B-8167-565DA602A919Q30405703-C4BFA1F0-1EFE-4278-8191-275D5D8C752CQ31091020-50ACF42E-1D53-45C3-B651-8E41A1CF1118Q33647074-C0FA22F4-AFB0-4380-9BD1-4AE64AC1A5F6Q33868731-5E1B1278-BD23-4B0D-9CD0-78E9519056A5Q33869797-F7FCC3CF-7A28-4B74-B1DF-FE4AEA719AE8Q33955338-AB2B6495-D38B-4FC2-9DCF-7DAFC64CA717Q34017067-79283383-0D89-46B7-943C-EADE814B2C84Q34044666-E162315A-56EC-465D-A572-96E786579826Q34763500-C2F12515-7D95-418E-B07F-46E72C402BB8Q34795807-6F1D9BD7-7595-4015-B3A9-0299A44A6228Q34896647-312BD885-7A47-494E-B699-28BC3323DA01Q34989010-07686F69-7F58-4749-B4A0-CA1EE5C71F69Q35053375-2B75812E-B86D-40C8-9AAD-40580BED7847Q35139434-C62E65EE-305F-4E4F-984C-4D4BF13AE1DAQ35173769-BC6D8FEB-43B0-424C-B558-18D2A5B6DABEQ35297286-9BDE32C4-2C0C-4FFF-84A3-FF49C1CFF570Q35666408-03D7171B-A407-461E-9AF5-8CE19291672EQ35666413-3A13FB0E-C996-4A6E-A985-EBA21E5018AAQ35781198-190FCA5D-3932-4A27-9DF8-DD0061E73F67Q36137272-FAC60447-B8BF-4FFD-9ADB-A29203CBB08FQ36502394-7CC8D658-A359-41CD-8C4B-847334637621Q36569426-24256C43-7798-4716-87F9-2A2E0933985FQ37107542-B64DDC77-C4D2-4772-9EC4-CAFC2A6AB79EQ37154488-74F18B43-E3D2-4FFB-9B77-D16D5AACB03FQ37263518-73CF5819-0732-4080-B892-344D802874ADQ37274674-C9C5ADF1-81B6-4DFB-9D41-D331BD72420EQ37321460-472110F0-B3C6-4311-8772-6563C3DBC2F0Q37325942-9B3EA718-D6D6-449A-967D-A289059B8FE6Q37340150-E7E20CE4-7CF8-409C-9CE5-7C465FAE4344Q37392936-FD3328E9-CBE9-47EC-89F0-4DC81BAF0D04Q37778941-4F30EA52-FCF3-42C8-8B9F-D7B88DC99C22Q37823878-0A793BC7-4573-47A7-926B-EA3A0549AA88Q37863657-B408E94B-65E7-4729-A92B-1ED195877385Q37875765-D87E7C67-1663-403D-8219-766760D84D99Q37877621-480F045B-57A2-43D1-B6DE-31739C6C7AADQ38028573-8E550BD8-E244-4E89-ADAF-B84323759A75Q38073892-CFD29F3E-CEA1-44AF-87DD-A9F8FB2BDAB7Q38105908-944FC0C2-18C5-48D8-B86D-E9BC205E0B23Q38137920-88AB1A5D-FD77-4DE4-B983-AEA4026418D3
P2860
Improved antimicrobial peptides based on acyl-lysine oligomers.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Improved antimicrobial peptides based on acyl-lysine oligomers.
@en
Improved antimicrobial peptides based on acyl-lysine oligomers.
@nl
type
label
Improved antimicrobial peptides based on acyl-lysine oligomers.
@en
Improved antimicrobial peptides based on acyl-lysine oligomers.
@nl
prefLabel
Improved antimicrobial peptides based on acyl-lysine oligomers.
@en
Improved antimicrobial peptides based on acyl-lysine oligomers.
@nl
P2093
P356
P1433
P1476
Improved antimicrobial peptides based on acyl-lysine oligomers
@en
P2093
Dmitry Bourdetsky
Inna S Radzishevsky
Shahar Rotem
Yehuda Carmeli
P2888
P304
P356
10.1038/NBT1309
P577
2007-05-27T00:00:00Z