Costimulatory blockade with mTor inhibition abrogates effector T-cell responses allowing regulatory T-cell survival in renal transplantation.
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Reviewing 15 years of experience with sirolimusMethylation of FOXP3 TSDR Underlies the Impaired Suppressive Function of Tregs from Long-term Belatacept-Treated Kidney Transplant PatientsBelatacept and sirolimus prolong nonhuman primate renal allograft survival without a requirement for memory T cell depletion.Pre-transplant donor-specific T-cell alloreactivity is strongly associated with early acute cellular rejection in kidney transplant recipients not receiving T-cell depleting induction therapyCD28 family and chronic rejection: "to belatacept...And beyond!".Preventing Allograft Rejection by Targeting Immune Metabolism.Fates of CD4+ T cells in a tolerant environment depend on timing and place of antigen exposure.B-Cell depletion and immunomodulation before initiation of enzyme replacement therapy blocks the immune response to acid alpha-glucosidase in infantile-onset Pompe disease.Belatacept: from rational design to clinical application.Rejection and regulation: a tight balance.Current pharmacotherapeutical options for the prevention of kidney transplant rejection.T-cell costimulatory blockade in organ transplantation.Current status of allograft tolerance in intestinal transplantation.Immunosuppressive minimization with mTOR inhibitors and belatacept.New perspectives on mTOR inhibitors (rapamycin, rapalogs and TORKinibs) in transplantation.Co-stimulation Blockade Plus T-Cell Depletion in Transplant Patients: Towards a Steroid- and Calcineurin Inhibitor-Free Future?Maintenance immunosuppressants in the management of antibody-mediated renal allograft rejection: which regimen is best?An mTOR-inhibitor-based protocol and calcineurin inhibitor (CNI)-free treatment in kidney transplant recipients from donors after cardiac death: good renal function, but high incidence of conversion to CNI.Safety of Intradiaphragmatic Delivery of Adeno-Associated Virus-Mediated Alpha-Glucosidase (rAAV1-CMV-hGAA) Gene Therapy in children affected by Pompe Disease.Generation and Characterization of Alloantigen-Specific Regulatory T Cells For Clinical Transplant Tolerance.Adoptive Cell Therapy with Tregs to Improve Transplant Outcomes: The Promise and the Stumbling Blocks.
P2860
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P2860
Costimulatory blockade with mTor inhibition abrogates effector T-cell responses allowing regulatory T-cell survival in renal transplantation.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
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2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
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2011年學術文章
@zh-hant
name
Costimulatory blockade with mT ...... ival in renal transplantation.
@en
Costimulatory blockade with mT ...... ival in renal transplantation.
@nl
type
label
Costimulatory blockade with mT ...... ival in renal transplantation.
@en
Costimulatory blockade with mT ...... ival in renal transplantation.
@nl
prefLabel
Costimulatory blockade with mT ...... ival in renal transplantation.
@en
Costimulatory blockade with mT ...... ival in renal transplantation.
@nl
P2093
P2860
P1476
Costimulatory blockade with mT ...... ival in renal transplantation.
@en
P2093
Joan Torras
Josep M Cruzado
Josep M Grinyó
Linda Cassis
Marc Lucia
Oriol Bestard
Salvador Gil-Vernet
P2860
P304
P356
10.1111/J.1432-2277.2011.01223.X
P577
2011-02-05T00:00:00Z