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Direct Activation of Bax Protein for Cancer TherapyNovel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent c-Met/ALK Multikinase Inhibitory Activities.Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists.BH4 domain of Bcl-2 as a novel target for cancer therapyExchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets.Discovery of novel 2,4-diarylaminopyrimidine analogues (DAAPalogues) showing potent inhibitory activities against both wild-type and mutant ALK kinases.Structure-activity relationships of 2-substituted phenyl-N-phenyl-2-oxoacetohydrazonoyl cyanides as novel antagonists of exchange proteins directly activated by cAMP (EPACs).Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic.Identification of novel 2-(benzo[d]isoxazol-3-yl)-2-oxo-N-phenylacetohydrazonoyl cyanide analoguesas potent EPAC antagonists.Selective Antagonists of the Bronchiolar Epithelial NF-κB-Bromodomain-Containing Protein 4 Pathway in Viral-Induced Airway Inflammation.Design, synthesis and pharmacological evaluation of 2-(thiazol-2-amino)-4-arylaminopyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.Design, synthesis, and pharmacological evaluation of benzamide derivatives as glucokinase activators.Mucosal Bromodomain-Containing Protein 4 (BRD4) Mediates Aeroallergen-induced Inflammation and RemodelingDiscovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammationIdentification of peptidomimetics as novel chemical probes modulating fibroblast growth factor 14 (FGF14) and voltage-gated sodium channel 1.6 (Nav1.6) protein-protein interactionsEfficacy of Novel Highly Specific Bromodomain-Containing Protein 4 Inhibitors in Innate Inflammation-Driven Airway RemodelingStructure-guided drug design identifies a BRD4-selective small molecule that suppresses HIVPharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodelingSynthesis and Biochemical Evaluation of Non-Cyclic Nucleotide Exchange Protein Directly Activated by cAMP 1 (EPAC1) Regulators
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Zhiqing Liu
@ast
Zhiqing Liu
@en
Zhiqing Liu
@es
Zhiqing Liu
@nl
Zhiqing Liu
@sl
type
label
Zhiqing Liu
@ast
Zhiqing Liu
@en
Zhiqing Liu
@es
Zhiqing Liu
@nl
Zhiqing Liu
@sl
prefLabel
Zhiqing Liu
@ast
Zhiqing Liu
@en
Zhiqing Liu
@es
Zhiqing Liu
@nl
Zhiqing Liu
@sl
P106
P31
P496
0000-0003-0266-6677