Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells.

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Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells.

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Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells.

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Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells.

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Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells.

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Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells.

@en

Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells.

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P1476

Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells.

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P2093

Emiko Fukumoto

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Hidetoshi Yamada

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Keiko Nakayama

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Lena Bosu

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Masaki Hosogane

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Soichiro Sato

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P2860

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

Geminin, an inhibitor of DNA replication, is degraded during mitosis

Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding

Geminin regulates neuronal differentiation by antagonizing Brg1 activity

Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint

Geminin promotes neural fate acquisition of embryonic stem cells by maintaining chromatin in an accessible and hyperacetylated state

DNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombination

Selective killing of cancer cells by suppression of geminin activity

Mechanisms to control rereplication and implications for cancer.

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360-375

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P31

scholarly article

P356

10.1111/GTC.12482

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P433

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P478

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P577

2017-03-14T00:00:00Z

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P698

28296014

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