The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs.
about
AML associated oncofusion proteins PML-RARA, AML1-ETO and CBFB-MYH11 target RUNX/ETS-factor binding sites to modulate H3ac levels and drive leukemogenesis.C/EBPα deregulation as a paradigm for leukemogenesis.RUNX1 cooperates with FLT3-ITD to induce leukemia.Combined HAT/EZH2 modulation leads to cancer-selective cell death.Cancer epigenetics: Moving forward.Long non-coding RNA RUNXOR accelerates MDSC-mediated immunosuppression in lung cancer.Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia.
P2860
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P2860
The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs.
description
2016 nî lūn-bûn
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2016年の論文
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年學術文章
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2016年學術文章
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name
The Hematopoietic Transcriptio ...... of the Apoptosis Program in t
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The Hematopoietic Transcriptio ...... tosis Program in t(8;21) AMLs.
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type
label
The Hematopoietic Transcriptio ...... of the Apoptosis Program in t
@nl
The Hematopoietic Transcriptio ...... tosis Program in t(8;21) AMLs.
@en
prefLabel
The Hematopoietic Transcriptio ...... of the Apoptosis Program in t
@nl
The Hematopoietic Transcriptio ...... tosis Program in t(8;21) AMLs.
@en
P2093
P1433
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The Hematopoietic Transcriptio ...... ptosis Program in t(8;21) AMLs
@en
P2093
Abhishek A Singh
Albertus T J Wierenga
Amit Mandoli
Edo Vellenga
Emile van den Akker
Esther Tijchon
Eva M Janssen-Megens
Filomena Matarese
Hendrik G Stunnenberg
P304
P356
10.1016/J.CELREP.2016.08.082
P577
2016-11-01T00:00:00Z