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Lack of phosphatidylethanolamine N-methyltransferase alters plasma VLDL phospholipids and attenuates atherosclerosis in miceHepatic phosphatidylethanolamine N-methyltransferase, unexpected roles in animal biochemistry and physiologyCholine supplementation promotes hepatic insulin resistance in phosphatidylethanolamine N-methyltransferase-deficient mice via increased glucagon actionImpaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesityFunctional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in miceValidation of an LC-MS/MS method for the quantification of choline-related compounds and phospholipids in foods and tissues.Feeding a Mixture of Choline Forms to Lactating Dams Improves the Development of the Immune System in Sprague-Dawley Rat Offspring.Novel insights on interactions between folate and lipid metabolism.A systematic review on the effect of sweeteners on glycemic response and clinically relevant outcomes.Differential expression of hypothalamic, metabolic and inflammatory genes in response to short-term calorie restriction in juvenile obese- and lean-prone JCR rats.Treatment with didemnin B, an elongation factor 1A inhibitor, improves hepatic lipotoxicity in obese miceExcess Folic Acid Increases Lipid Storage, Weight Gain, and Adipose Tissue Inflammation in High Fat Diet-Fed RatsThe critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease.Cystathionine beta-synthase deficiency alters hepatic phospholipid and choline metabolism: Post-translational repression of phosphatidylethanolamine N-methyltransferase is a consequence rather than a cause of liver injury in homocystinuria.The concentration of phosphatidylethanolamine in mitochondria can modulate ATP production and glucose metabolism in mice.Impact of Egg Consumption on Cardiovascular Risk Factors in Individuals with Type 2 Diabetes and at Risk for Developing Diabetes: A Systematic Review of Randomized Nutritional Intervention Studies.A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoansPioglitazone attenuates hepatic inflammation and fibrosis in phosphatidylethanolamine N-methyltransferase-deficient mice.Measurement of the abundance of choline and the distribution of choline-containing moieties in meat.Alterations in skeletal muscle fatty acid handling predisposes middle-aged mice to diet-induced insulin resistance.Feeding a Mixture of Choline Forms during Lactation Improves Offspring Growth and Maternal Lymphocyte Response to Ex Vivo Immune Challenges.Decreased lipogenesis in white adipose tissue contributes to the resistance to high fat diet-induced obesity in phosphatidylethanolamine N-methyltransferase-deficient mice.Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferaseTissue Specific Effects of Dietary Carbohydrates and Obesity on ChREBPα and ChREBPβ Expression.Insufficient glucose supply is linked to hypothermia upon cold exposure in high-fat diet-fed mice lacking PEMT.Tamoxifen induces triacylglycerol accumulation in the mouse liver by activation of fatty acid synthesis.Hepatic ratio of phosphatidylcholine to phosphatidylethanolamine predicts survival after partial hepatectomy in mice.Choline supplementation protects against liver damage by normalizing cholesterol metabolism in Pemt/Ldlr knockout mice fed a high-fat diet.Targeted deletion of hepatic CTP:phosphocholine cytidylyltransferase alpha in mice decreases plasma high density and very low density lipoproteins.Endoplasmic reticulum-localized hepatic lipase decreases triacylglycerol storage and VLDL secretion.Physiological regulation of phospholipid methylation alters plasma homocysteine in mice.Dietary creatine supplementation lowers hepatic triacylglycerol by increasing lipoprotein secretion in rats fed high-fat diet.Riboflavin Deficiency in Rats Decreases de novo Formate Production but Does Not Affect Plasma Formate Concentration.Vagus nerve contributes to the development of steatohepatitis and obesity in phosphatidylethanolamine N-methyltransferase deficient mice.Folate, vitamin B12, and vitamin B6 status of a group of high socioeconomic status women in the Alberta Pregnancy Outcomes and Nutrition (APrON) cohort.Interactions between the consumption of a high-fat diet and fasting in the regulation of fatty acid oxidation enzyme gene expression: an evaluation of potential mechanisms.Lack of phosphatidylethanolamine N-methyltransferase in mice does not promote fatty acid oxidation in skeletal muscle.The dietary form of choline during lactation affects maternal immune function in rats.Lack of phosphatidylethanolamine N-methyltransferase alters hepatic phospholipid composition and induces endoplasmic reticulum stress.Choline deficiency impairs intestinal lipid metabolism in the lactating rat.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
René L Jacobs
@nl
René L Jacobs
@sl
René L. Jacobs
@en
René L. Jacobs
@es
type
label
René L Jacobs
@nl
René L Jacobs
@sl
René L. Jacobs
@en
René L. Jacobs
@es
prefLabel
René L Jacobs
@nl
René L Jacobs
@sl
René L. Jacobs
@en
René L. Jacobs
@es
P106
P1153
7401996608
P21
P31
P496
0000-0002-5525-1355