about
An albumin-derived peptide scaffold capable of binding and catalysisA competitive immunoassay for the detection of esterolytic activity of antibodies and enzymes.The isopeptidase inhibitor 2cPE triggers proteotoxic stress and ATM activation in chronic lymphocytic leukemia cells.Impact of Stereochemistry on Ligand Binding: X-ray Crystallographic Analysis of an Epoxide-Based HIV Protease Inhibitor.Chlorogenic Compounds from Coffee Beans Exert Activity against Respiratory Viruses.The non-peptidic HIV protease inhibitor tipranavir and two synthetic peptidomimetics (TS98 and TS102) modulate Pneumocystis carinii growth and proteasome activity of HEL299 cell line.Synthesis and biological evaluation in vitro and in mammalian cells of new heteroaryl carboxyamides as HIV-protease inhibitors.Design of peptidomimetic inhibitors of aspartic protease of HIV-1 containing -Phe Psi Pro- core and displaying favourable ADME-related properties.Synthesis and biological activity of potent HIV-1 protease inhibitors based on Phe-Pro dihydroxyethylene isosteres.GRID/tetrahedral intermediate computational approach to the study of selectivity of penicillin G acylase in amide bond synthesis.Epoxyalcohol route to hydroxyethylene dipeptide isosteres. Stereodivergent synthesis of the diamino alcohol core of ritonavir and its C-2 epimer.A catalytic antibody programmed for torsional activation of amide bond hydrolysis.Small hydroxyethylene-based peptidomimetics inhibiting both HIV-1 and C. albicans aspartic proteases.Aldolase activity of serum albumins.Efficient chemoenzymatic synthesis of chiral pincer ligands.Synthesis, characterization, and optimization for in vivo delivery of a nonselective isopeptidase inhibitor as new antineoplastic agent.Purification and characterization of l,(l/d)-aminopeptidase from Guinea pig serum.The binding landscape of a partially-selective isopeptidase inhibitor with potent pro-death activity, based on the bis(arylidene)cyclohexanone scaffold.Designing Short Peptides with High Affinity for Organic Molecules: A Combined Docking, Molecular Dynamics, And Monte Carlo Approach.Synthesis of a Val-Pro diaminodiol dipeptide isostere by epoxyamine cyclization.Addressing the Poly- to Oligo-ketone Selectivity in Styrene Carbonylation Catalyzed by Palladium/bpy Complexes. Effect of the 6-Alkyl SubstitutionA Potent HIV Protease Inhibitor Identified in an Epimeric Mixture by High-Resolution Protein CrystallographyEfficient Biginelli Synthesis of 2-Aminodihydropyrimidines under Microwave IrradiationCorrigendum to “Fluorescent molecularly imprinted nanogels for the detection of anticancer drugs in human plasma” [Biosens. Bioelectron. 86 (2016) 913–919]Synthesis of Chiral, Enantiopure Allylic Amines by the Julia Olefination of α-Amino EstersFluorescent molecularly imprinted nanogels for the detection of anticancer drugs in human plasmaAlbumin-directed stereoselective reduction of 1,3-diketones and β-hydroxyketones to anti diolsSynthesis and Biological Activity of New Mixed HIV-PR Inhibitors Conjugated to Bifunctional High-Molecular Weight Poly(Ethylene Glycol)Chiral Pincer Ruthenium and Osmium Complexes for the Fast and Efficient Hydrogen Transfer Reduction of KetonesSynthesis and application of new mixed, polymer-conjugated drugs. Use of selectively end-modified poly(ethylene glycol)Development and evaluation of an immunoassay for the monitoring of the anti-HIV drug amprenavirStereoselective Hydroazidation of Amino Enones: Synthesis of the Ritonavir/Lopinavir CoreStructure Based Design of Inhibitors of Aspartic Protease of HIV-1An Unprecedented Catalytic Motif Revealed in the Model Structure of Amide Hydrolyzing Antibody 312d6Unexpected 1,2,3-triazole formation in the reaction of diethylaluminum azide with α′-amino-α,β-unsaturated ketonesVal-Ala Dipeptide Isosteres by Hydrocyanation of α′-Amino α,β-Unsaturated Ketones − Control of Stereoselectivity by the N-Protecting GroupAlbumin-controlled stereoselective reduction of 1,3-diketones to anti-diolsElectronic supplementary information (ESI) available: Scatchard and Lineweaver–Burk plots. See http://www.rsc.org/suppdata/cc/b2/b200474g/A study of the molecular structure and spectroscopic properties of polycyclic polyaza-compounds with diamond-lattice conformationsAntibody catalyzed modification of amino acids. Efficient hydrolysis of tyrosine benzoateEpoxyalcohol route to hydroxyethylene dipeptide isosteres: a new synthesis of the diaminoalcohol core of HIV-protease inhibitor ABT-538 (Ritonavir)
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Fabio Benedetti
@ast
Fabio Benedetti
@en
Fabio Benedetti
@es
Fabio Benedetti
@nl
Fabio Benedetti
@sl
type
label
Fabio Benedetti
@ast
Fabio Benedetti
@en
Fabio Benedetti
@es
Fabio Benedetti
@nl
Fabio Benedetti
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altLabel
Fabio Benedetti
@en
prefLabel
Fabio Benedetti
@ast
Fabio Benedetti
@en
Fabio Benedetti
@es
Fabio Benedetti
@nl
Fabio Benedetti
@sl
P1053
G-4787-2012
P106
P1153
36729710000
P21
P31
P3829
P496
0000-0002-8773-7413